Results 21 to 30 of about 968 (131)

Two decades of occurrence of non-pathogenic rabbit lagoviruses in Italy and their genomic characterization [PDF]

Scientific Reports
Lagoviruses are viruses of the Caliciviridae family affecting lagomorphs. Both pathogenic and non-pathogenic lagoviruses affect the European rabbit (Oryctolagus cuniculus), and they are phylogenetically distinguished.
Patrizia Cavadini, Alice Vismarra, Francesca Merzoni, Vittoria Di Giovanni, Maria Beatrice Boniotti, Lorenzo Capucci, Antonio Lavazza   +6 more
doaj   +2 more sources

Digital PCR (dPCR) Quantification of miR-155-5p as a Potential Candidate for a Tissue Biomarker of Inflammation in Rabbits Infected with Lagovirus europaeus/Rabbit Hemorrhagic Disease Virus (RHDV). [PDF]

Viruses, 2023
MicroRNAs (miRNAs, miRs) are a group of small, 17–25 nucleotide, non-coding RNA sequences that, in their mature form, regulate gene expression at the post-transcriptional level. They participate in many physiological and pathological processes in both humans and animals.
Hukowska-Szematowicz B, Ostrycharz E, Dudzińska W, Roszkowska P, Siennicka A, Wojciechowska-Koszko I.   +5 more
europepmc   +4 more sources

Epitope mapping of a neutralizing antibody against rabbit hemorrhagic disease virus GI.2 [PDF]

Veterinary Research
In 2010, rabbit hemorrhagic disease virus (RHDV) GI.2 emerged, and unlike RHDV GI.1, it caused mortality in young rabbits, while existing vaccines were not fully protective.
Ana Podadera, Mila Leuthold, José Manuel Martín-Alonso, Rosa Casais, Angel Luis Álvarez, M. J. Lobo-Castañón, Francisco Parra, Kevin Paul Dalton   +7 more
doaj   +2 more sources

Production, Characterization, and Epitope Mapping of Monoclonal Antibodies Against Different Subtypes of Rabbit Hemorrhagic Disease Virus (RHDV). [PDF]

Sci Rep, 2016
AbstractIn 2010, a new rabbit hemorrhagic disease virus (RHDV) variant, designated RHDV2, was identified for the first time in Italy. Studies have shown that RHDV2 differs from RHDV1 (traditional RHDV) in terms of its antigenic profile and genetic characteristics.
Kong D, Liu J, Jiang Q, Yu Z, Hu X, Guo D, Huang Q, Jiao M, Qu L.   +8 more
europepmc   +4 more sources

Comparative analysis of rabbit hemorrhagic disease virus (RHDV) and new RHDV2 virus antigenicity, using specific virus-like particles. [PDF]

Vet Res, 2015
In 2010 a new Lagovirus related to rabbit haemorrhagic disease virus (RHDV) emerged in France and has since rapidly spread throughout domestic and wild rabbit populations of several European countries. The new virus, termed RHDV2, exhibits distinctive genetic, antigenic and pathogenic features.
Bárcena J, Guerra B, Angulo I, González J, Valcárcel F, Mata CP, Castón JR, Blanco E, Alejo A.   +8 more
europepmc   +6 more sources

Detection and Characterisation of The 'A' Variant of Rabbit Haemorrhagic Disease (RHDVa, GI.1a) Over a Decade (2013-2023) in Italy. [PDF]

Transbound Emerg Dis
Since the 1980s, highly pathogenic and hepatotropic Lagovirus species have significantly impacted rabbit populations, including Rabbit Haemorrhagic Disease Virus (RHDV, genotype GI.1), its variant RHDVa (genotype GI.1a), and RHDV type 2 (RHDV2, genotype GI.2).
Di Giovanni V, Bazzucchi M, Capucci L, Lavazza A, Cavadini P.   +4 more
europepmc   +2 more sources

Development of a SYBR-based real-time PCR to detect rabbit hemorrhagic disease virus (RHDV) and analyze its tissue distribution in experimentally infected rabbits. [PDF]

Virol Sin, 2015
In this study, we developed a real-time PCR assay for RHDV detection and quantitation. With this method, the distribution of RHDV in the internal organs and body fluids of infected rabbits was analyzed. The highest viral RNA load was found in the spleen, followed by that in the liver.
Liu W, Dang R, Wang X.
europepmc   +4 more sources

Diagnosis of a Rabbit Hemorrhagic Disease Virus 2 (RHDV2) and the Humoral Immune Protection Effect of VP60 Vaccine

Current Issues in Molecular Biology, 2023
Rabbit hemorrhagic disease (RHD) is known as rabbit plague and hemorrhagic pneumonia. It is an acute, septic, and highly fatal infectious disease caused by the Lagovirus rabbit hemorrhagic disease virus (RHDV) in the family Caliciviridae that infects ...
Zhaoming Li, Kaimin Song, Yongzhen Du, Zhuanglong Zhang, Rupeng Fan, Pimiao Zheng, Jianzhu Liu   +6 more
doaj   +1 more source

Molecular docking insights of Nigella sativa compounds as potential antiviral inhibitory agents against the replication-machinery proteins VPg and RdRP in rabbit hemorrhagic disease virus (RHDV). [PDF]

Virol J
Abstract The Rabbit Hemorrhagic Disease Virus (RHDV) represents a significant threat to rabbit populations globally, affecting both wild and domesticated rabbits, with mortality rates ranging from 50% to 90%. Despite its severity, there is currently no specific treatment available for RHDV.
Afifi YR, El-Akkad TA, Badr OA, Ibrahim SD, Serag AM.   +4 more
europepmc   +3 more sources

Occurrence of Lagovirus europaeus (Rabbit Hemorrhagic Disease Virus) in Domestic Rabbits in Southwestern Poland in 2019: Case Report

Microbiology Spectrum, 2022
Lagovirus europaeus (rabbit hemorrhagic disease virus [RHDV]) is a small, nonenveloped, single-stranded RNA virus that causes a severe, highly infectious, and fatal disease in rabbits (Oryctolagus cuniculus) called rabbit hemorrhagic disease (RHD). Since
Rafał Hrynkiewicz, Dominika Bębnowska, Ari Kauppinen, Tuija Gadd, Tomasz Piasecki, Paulina Niedźwiedzka-Rystwej   +5 more
doaj   +1 more source