Results 21 to 30 of about 1,602 (176)

The Baculovirus Expression System Expresses Chimeric RHDV VLPs as Bivalent Vaccine Candidates for Classic RHDV (GI.1) and RHDV2 (GI.2) [PDF]

Vaccines
Background: Rabbit hemorrhagic disease (RHD) is an acute, hemorrhagic and highly lethal infectious disease caused by rabbit hemorrhagic disease virus (RHDV), which causes huge economic losses to the rabbit breeding industry.
Yan Wang, Yiyang Fan, Ruixiang Bi, Yapeng Zhao, Wanning Gao, Derong Zhang, Jialin Bai   +6 more
doaj   +2 more sources

Development of a SYBR-based real-time PCR to detect rabbit hemorrhagic disease virus (RHDV) and analyze its tissue distribution in experimentally infected rabbits. [PDF]

Virol Sin, 2015
In this study, we developed a real-time PCR assay for RHDV detection and quantitation. With this method, the distribution of RHDV in the internal organs and body fluids of infected rabbits was analyzed. The highest viral RNA load was found in the spleen, followed by that in the liver.
Liu W, Dang R, Wang X.
europepmc   +4 more sources

Molecular docking insights of Nigella sativa compounds as potential antiviral inhibitory agents against the replication-machinery proteins VPg and RdRP in rabbit hemorrhagic disease virus (RHDV). [PDF]

Virol J
Abstract The Rabbit Hemorrhagic Disease Virus (RHDV) represents a significant threat to rabbit populations globally, affecting both wild and domesticated rabbits, with mortality rates ranging from 50% to 90%. Despite its severity, there is currently no specific treatment available for RHDV.
Afifi YR, El-Akkad TA, Badr OA, Ibrahim SD, Serag AM.   +4 more
europepmc   +2 more sources

Rabbit Hemorrhagic Disease Virus 2 (RHDV2; GI.2) Is Replacing Endemic Strains of RHDV in the Australian Landscape within 18 Months of Its Arrival [PDF]

Journal of Virology, 2018
ABSTRACT Rabbit hemorrhagic disease virus 2 (RHDV2; Lagovirus GI.2) is a pathogenic calicivirus that affects European rabbits ( Oryctolagus cuniculus ) and various hare ( Lepus ) species.
Jackie E. Mahar, Robyn N. Hall, David Peacock, John Kovaliski, Melissa Piper, Roslyn Mourant, Nina Huang, Susan Campbell, Xingnian Gu, Andrew Read, Nadya Urakova, Tarnya Cox, Edward C. Holmes, Tanja Strive   +13 more
openaire   +5 more sources

RNAi Inhibition of Rabbit Hemorrhagic Disease Virus (RHDV) Gene Expression in CHO Cell Line [PDF]

مجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2008
Rabbit hemorrhagic disease virus (RHDV) causes great losses and is life threatening to both wild and domestic rabbits. This work represents the first step toward production of transgenic rabbits resistant to RHDV by RNAi through the inhibition of ...
Bilal Ghareeb
doaj   +2 more sources

Codon optimization of the rabbit hemorrhagic disease virus (RHDV) capsid gene leads to increased gene expression in Spodoptera frugiperda 9 (Sf9) cells. [PDF]

J Vet Sci, 2013
Rabbit hemorrhagic disease (RHD) is contagious and highly lethal. Commercial vaccines against RHD are produced from the livers of experimentally infected rabbits. Although several groups have reported that recombinant subunit vaccines against rabbit hemorrhagic disease virus (RHDV) are promising, application of the vaccines has been restricted due to ...
Gao J, Meng C, Chen Z, Li C, Liu G.
europepmc   +3 more sources

Rabbit Hemorrhagic Disease Virus Non-structural Protein 6 Induces Apoptosis in Rabbit Kidney Cells

Frontiers in Microbiology, 2019
Rabbit hemorrhagic disease (RHD) is a highly contagious disease caused by rabbit hemorrhagic disease virus (RHDV). Previous research has shown that RHDV induces apoptosis in numerous cell types, although the molecular mechanisms underlying the apoptosis ...
Mengmeng Chen, Xing Liu, Bo Hu, Zhiyu Fan, Yanhua Song, Houjun Wei, Rulong Qiu, Weizhong Xu, Weifeng Zhu, Fang Wang   +9 more
doaj   +3 more sources

In vitro translation of a subgenomic mRNA from purified virions of the Spanish field isolate AST/89 of Rabbit Hemorrhagic Disease Virus (RHDV)

Virus Research, 1992
Purified preparations of the Spanish field isolate of rabbit hemorrhagic disease virus AST/89 were found to contain the plus-stranded genomic RNA of more than 7.4 kilobases (kb) and large amounts of a subgenomic mRNA of 2.4 kb. The smaller RNA was translated in vitro and shown to code for a 60 kDa protein which was immunoprecipitated using anti-RHDV as
Boga, JoséAntonio, Marín, María Soledad, Casais, Rosa, Prieto, Miguel, Parra, Francisco   +4 more
openaire   +4 more sources

Case series: Four fatal rabbit hemorrhagic disease virus infections in urban pet rabbits

Frontiers in Veterinary Science, 2023
Four pet rabbits (Oryctolagus cuniculus cuniculus) diagnosed with a fatal infection by rabbit hemorrhagic disease virus (RHDV GI.2) were identified in the same week and further investigated.
Filipe Fontes Pinto, Filipe Fontes Pinto, Filipe Fontes Pinto, Filipe Fontes Pinto, Joana Abrantes, Joana Abrantes, Joana Abrantes, Paula Gomes Ferreira, Paula Gomes Ferreira, Paula Gomes Ferreira, Mário Nóbrega, Ricardo Marcos   +11 more
doaj   +3 more sources

Two decades of occurrence of non-pathogenic rabbit lagoviruses in Italy and their genomic characterization [PDF]

Scientific Reports
Lagoviruses are viruses of the Caliciviridae family affecting lagomorphs. Both pathogenic and non-pathogenic lagoviruses affect the European rabbit (Oryctolagus cuniculus), and they are phylogenetically distinguished.
Patrizia Cavadini, Alice Vismarra, Francesca Merzoni, Vittoria Di Giovanni, Maria Beatrice Boniotti, Lorenzo Capucci, Antonio Lavazza   +6 more
doaj   +2 more sources