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Rabbit Haemorrhagic Disease Virus 2 (RHDV2; GI.2) in Ireland Focusing on Wild Irish Hares (Lepus timidus hibernicus): An Overview of the First Outbreaks and Contextual Review

open access: yesPathogens, 2022
Rabbit haemorrhagic disease virus 2 (RHDV2; GI.2) is a pathogenic lagovirus that emerged in 2010, and which now has a global distribution. Outbreaks have been associated with local population declines in several lagomorph species, due to rabbit ...
Andrew W. Byrne   +6 more
doaj   +1 more source

Passive Immunisation against RHDV2 Induces Protection against Disease but Not Infection

open access: yesVaccines, 2021
Rabbit haemorrhagic disease virus 2 (RHDV2) is a lagovirus in the family Caliciviridae. The closely related Rabbit haemorrhagic disease virus (RHDV, termed RHDV1 throughout this manuscript for clarity) has been used extensively as a biocontrol agent in ...
Robyn N. Hall   +6 more
doaj   +1 more source

Genetic Evolution and Biological Characteristics of Feline Caliciviruses Isolated from Dogs

open access: yesTransboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
Feline calicivirus (FCV) is a highly contagious pathogen associated with oral and upper respiratory tract diseases (URTD), and it is also possibly considered as an enteric pathogen. Some studies found FCV‐like viruses in the enteric tract of dogs, but there was a lack of understanding regarding the epidemiology and biological properties of FCVs in dogs.
Fanyuan Sun   +17 more
wiley   +1 more source

Immune response in the recombinant strain of Lagovirus europaeus GI.1a

open access: yesInfection, Genetics and Evolution, 2023
Lagovirus europaeus/GI.1 is the virus that causes severe and dangerous rabbit haemorrhagic disease (RHD) in rabbits. Recombination formation in RHD viruses is common. Recombination is thought to play a key role in the evolution of lagoviruses and therefore most likely influences the pathogenicity of L. europaeus/GI strains.
Dominika, Bębnowska   +3 more
openaire   +2 more sources

Age and Infectious Dose Significantly Affect Disease Progression after RHDV2 Infection in Naïve Domestic Rabbits

open access: yesViruses, 2021
Rabbit haemorrhagic disease virus 2 (RHDV2 or GI.2, referring to any virus with lagovirus GI.2 structural genes) is a recently emerged calicivirus that causes generalised hepatic necrosis and disseminated intravascular coagulation leading to death in ...
Robyn N. Hall   +8 more
doaj   +1 more source

An RT‐qPCR Assay from Rectal Swabs for the Detection of Rabbit Hemorrhagic Disease Virus 2 in Natural Cases

open access: yesTransboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
Rabbit hemorrhagic disease virus 2 (RHDV2 or Lagovirus europaeus GI.2) is spreading across North America. This has enabled submissions of lagomorphs for testing to veterinary diagnostic laboratories (VDLs). The liver is currently the gold‐standard sample type for testing by RT‐qPCR.
Javier Asin   +7 more
wiley   +1 more source

Potent Protease Inhibitors of Highly Pathogenic Lagoviruses: Rabbit Hemorrhagic Disease Virus and European Brown Hare Syndrome Virus

open access: yesMicrobiology Spectrum, 2022
Rabbit hemorrhagic disease (RHD) and European brown hare syndrome (EBHS) are highly contagious diseases caused by lagoviruses in the Caliciviridae family.
Krishani Dinali Perera   +5 more
doaj   +1 more source

High Mortality of Wild European Rabbits during a Natural Outbreak of Rabbit Haemorrhagic Disease GI.2 Revealed by a Capture‐Mark‐Recapture Study

open access: yesTransboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
Rabbit haemorrhagic disease virus (RHDV) GI.2 has caused significant declines in the abundance of wild European rabbits (Oryctolagus cuniculus), contributing to the species being recently classified as “endangered” in its native range. The epidemiology of this virus is still poorly understood despite its relevance for domestic and wild rabbits.
Saúl Jiménez-Ruiz   +7 more
wiley   +1 more source

Immunological Cross-Protection between Different Rabbit Hemorrhagic Disease Viruses—Implications for Rabbit Biocontrol and Vaccine Development

open access: yesVaccines, 2022
The use of rabbit hemorrhagic disease virus (RHDV) as a biocontrol agent to control feral rabbit populations in Australia, in combination with circulating endemic strains, provides a unique environment to observe the interactions between different ...
Tiffany W. O’Connor   +4 more
doaj   +1 more source

Novel Recombinant Rabbit Hemorrhagic Disease Virus 2 (RHDV2) is Circulating in China within 12 Months after Original RHDV2 Arrival

open access: yesTransboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
Rabbit hemorrhagic disease (RHD) causes lethal fulminant hepatitis in rabbits. Two different genotypes (GI.1 and GI.2) responsible for RHD are reported. GI.2 was first detected in France in 2010 and subsequently spread to other countries in Europe. In April 2020, GI.2 was detected in China.
Bo Hu   +9 more
wiley   +1 more source

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