Immunity against Lagovirus europaeus and the Impact of the Immunological Studies on Vaccination [PDF]
In the early 1980s, a highly contagious viral hemorrhagic fever in rabbits (Oryctolagus cuniculus) emerged, causing a very high rate of mortality in these animals.
Claudia Müller +6 more
doaj +5 more sources
Digital PCR (dPCR) Quantification of miR-155-5p as a Potential Candidate for a Tissue Biomarker of Inflammation in Rabbits Infected with Lagovirus europaeus/Rabbit Hemorrhagic Disease Virus (RHDV) [PDF]
MicroRNAs (miRNAs, miRs) are a group of small, 17–25 nucleotide, non-coding RNA sequences that, in their mature form, regulate gene expression at the post-transcriptional level.
Beata Hukowska-Szematowicz +5 more
doaj +4 more sources
Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures [PDF]
Vesivirus 2117 is an adventitious agent that in 2009, was identified as a contaminant of CHO cells propagated in bioreactors at a pharmaceutical manufacturing plant belonging to Genzyme.
Bhella, David +8 more
core +5 more sources
Serological characterisation of Lagovirus virus-like particles originating from native and mutated VP60 of rabbit haemorrhagic disease virus 2 and European brown hare syndrome virus [PDF]
Since lagoviruses cannot be cultivated in vitro, using expression systems is an alternative and promising way of producing diagnostic viral antigens. It opens up their use as active immunogens for vaccine production.
Krejmer-Rąbalska Martyna +3 more
doaj +3 more sources
Rabbit haemorrhagic disease (RHD) was first detected in 1984 and quickly spread among wild and domestic European rabbits (Oryctolagus cuniculus) throughout the world. RHD and European brown hare syndrome (EBHS), a related disease of hares (Lepus spp.), are caused by pathogenic lagoviruses of the Family Caliciviridae.
Ayako Miyazaki
exaly +6 more sources
Emergence of a new lagovirus related to rabbit haemorrhagic disease virus [PDF]
Since summer 2010, numerous cases of Rabbit Haemorrhagic Disease (RHD) have been reported in north-western France both in rabbitries, affecting RHD-vaccinated rabbits, and in wild populations. We demonstrate that the aetiological agent was a lagovirus phylogenetically distinct from other lagoviruses and which presents a unique antigenic profile ...
Ghislaine Le Gall-Reculé +2 more
exaly +8 more sources
Rabbit Haemorrhagic Disease Virus (RHDV), which is a calicivirus, is used as a biocontrol agent to suppress European wild rabbit populations in Australia.
Emma Sawyers +4 more
doaj +4 more sources
Recombination at the emergence of the pathogenic rabbit haemorrhagic disease virus Lagovirus europaeus/GI.2 [PDF]
AbstractRabbit haemorrhagic disease is a viral disease that emerged in the 1980s and causes high mortality and morbidity in the European rabbit (Oryctolagus cuniculus). In 2010, a new genotype of the rabbit haemorrhagic disease virus emerged and replaced the former circulating Lagovirus europaeus/GI.1 strains.
Joana Abrantes +2 more
exaly +4 more sources
Utilizing Molecular Epidemiology and Citizen Science for the Surveillance of Lagoviruses in Australia [PDF]
Australia has multiple lagoviruses with differing pathogenicity. The circulation of these viruses was traditionally determined through opportunistic sampling events. In the lead up to the nationwide release of RHDVa-K5 (GI.1aP-GI.1a) in 2017, an existing
Nias Y. G. Peng +14 more
doaj +2 more sources
Characterisation of Lagovirus europaeus GI-RHDVs (Rabbit Haemorrhagic Disease Viruses) in Terms of Their Pathogenicity and Immunogenicity. [PDF]
Rabbit haemorrhagic disease viruses (RHDV) belong to the family Caliciviridae, genus Lagovirus europaeus, genogroup GI, comprising four genotypes GI.1–GI.4, of which the genotypes GI.1 and GI.2 are pathogenic RHD viruses, while the genotypes GI.3 and GI.4 are non-pathogenic RCV (Rabbit calicivirus) viruses.
Tokarz-Deptuła B +4 more
europepmc +5 more sources

