Comparative analysis of the extent of protein–protein interactions in icosahedral viral capsids
Abstract Nonenveloped viruses package, carry, and deliver their genomes to the targeted cells using protein shells known as capsids. The viral capsids come in different shapes and sizes, most exhibiting helical or icosahedral symmetries. Here, we analyzed 634 icosahedral capsids at high resolution (<4 Å) from 39 virus families with T‐numbers ranging ...
Noah J. Zimmerman +2 more
wiley +1 more source
In Vitro Antiviral and Virucidal Activity of Ozone against Feline Calicivirus
The Caliciviridae family includes several viral pathogens of humans and animals, including norovirus (NoV), genus Norovirus, and feline calicivirus (FCV), genus Vesivirus.
Cristiana Catella +10 more
doaj +1 more source
Interferon-lambda: A potent regulator of intestinal viral infections [PDF]
Interferon-lambda (IFN-λ) is a recently described cytokine found to be of critical importance in innate immune regulation of intestinal viruses. Endogenous IFN-λ has potent antiviral effects and has been shown to control multiple intestinal viruses and ...
Baldridge, Megan T, Lee, Sanghyun
core +3 more sources
Hepatitis E virus: a zoonosis adapting to humans [PDF]
Hepatitis E virus (HEV) infection is gaining global attention, not only because of the increasing burden of the disease in low endemicity countries, in terms of morbidity and mortality rates, but also due to recent advances in the molecular virology and ...
Bihl, Florian, Negro, Francesco
core
Near-Complete Genome Sequences of Several New Norovirus Genogroup II Genotypes. [PDF]
We report here the near-complete genome sequences of 13 norovirus strains detected in stool samples from patients with acute gastroenteritis from Bangladesh, Ecuador, Guatemala, Peru, Nicaragua, and the United States that are classified into one existing
Ahmed, T +13 more
core +1 more source
Diagnostic electron microscopy in human infectious diseases – Methods and applications
Abstract Diagnostic electron microscopy (EM) is indispensable in all cases of infectious diseases which deserve or profit from the detection of the entire pathogen (i.e. the infectious unit). The focus of its application has shifted during the last decades from routine diagnostics to diagnostics of special cases, emergencies and the investigation of ...
Michael Laue
wiley +1 more source
In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase [PDF]
Human norovirus causes approximately 219,000 deaths annually, yet there are currently no antivirals available. A virtual screening of commercially available drug-like compounds (~300,000) was performed on the suramin and PPNDS binding-sites of the ...
Ferla, Salvatore +8 more
core +3 more sources
Immune response to norovirus infection
Noroviruses are non-enveloped viruses of the family Caliciviridae. The norovirus variants that infect humans are highly contagious and are a leading cause of outbreaks for nonbacterial gastroenteritis. In the etiological pattern of acute viral intestinal
Vladimir Y. Talayev +5 more
doaj +1 more source
EPIDEMIOLOGY OF VIRAL GASTROENTERITIS IN IRAN [PDF]
Viruses are prominent causative agents of acute gastroenteritis in children
Jalilvand, Somayeh. +3 more
core +1 more source
Enteroviruses in Water: Epidemiology, Detection and Inactivation
In this review, enterovirus presence and persistence in water are described. The epidemiology, detection and monitoring and control of enteroviruses are discussed. ABSTRACT Enteroviruses are small non‐enveloped RNA viruses commonly found in environmental water samples.
Corentin Morvan +5 more
wiley +1 more source

