Construction of Reverse Genetics System for Feline Calicivirus FCV-BJ616 and Proteomic Analysis. [PDF]
This study successfully isolated the FCV‐BJ616 strain derived from cats and established a reverse genetics system. In vivo experiments showed that rFCV‐BJ616 exhibits wild‐type virulence, leading to high fever, weight loss, and multi‐organ lesions in infected cats. Proteomic analysis indicated that both rFCV‐BJ616 and FCV‐BJ616 share similar regulatory
Xu C +9 more
europepmc +2 more sources
Engineered VP1 mRNA Vaccine Induces Immunity and Complete Protection Against Feline Calicivirus in Cats. [PDF]
Feline calicivirus (FCV) is a major pathogen of upper respiratory tract diseases in cats, posing a significant threat to feline health. While current FCV preventive measures rely primarily on traditional vaccines, messenger RNA (mRNA) vaccines have emerged as a promising alternative, offering high efficacy, safety, rapid clinical development, and ...
Zhang MD +13 more
europepmc +2 more sources
Transcriptomic analysis of Crandell-Rees feline kidney cell infections with field and vaccine feline calicivirus strains [PDF]
Feline upper respiratory tract disease (URTD) is a significant health concern in crowded environments, such as catteries and shelters. Feline calicivirus (FCV), which is endemic in domestic cats, is a major contributor to URTD and can cause a range of ...
Emily Kwan +3 more
doaj +2 more sources
Epidemiology, Phylogenetic Divergence, and Differential Pathogenicity of Feline Respiratory <i>Mycoplasma</i> in China. [PDF]
Mycoplasma felis (M. felis) is a wall‐less pathogen known to induce respiratory diseases in felines. Current research on respiratory M. felis infections is scant, lacking established typing system and nationwide epidemiological survey. This study investigated the prevalence of M.
Ye Z +8 more
europepmc +2 more sources
The Enhancement of Immunity Gained from Feline Trivalent Vaccines in Mice Using Feline IL-15, IL-23 and Metabolic Regulatory Molecules [PDF]
The feline calicivirus, herpesvirus, and panleukopenia viruses are major infections that cause serious diseases in cats; however, current trivalent vaccines have limitations in immune efficacy and their duration of protection.
Ruichen Gao +8 more
doaj +2 more sources
The quadruplex TaqMan MGB fluorescent quantitative PCR method for simultaneous detection of feline panleukopenia virus, feline herpesvirus 1, feline calicivirus and feline infectious peritonitis virus [PDF]
BackgroundFeline panleukopenia, feline calicivirus infection, feline viral rhinotracheitis, and feline infectious peritonitis are significant diseases that threaten feline health.
Haojie Wang +10 more
doaj +2 more sources
Viral Coinfections Potentially Associated with Feline Chronic Gingivostomatitis in Cats with Feline Infectious Peritonitis [PDF]
Feline infectious peritonitis (FIP) is a fatal but now treatable disease in cats caused by feline coronavirus (FCoV). This study prospectively investigated viral coinfections in 100 cats diagnosed with FIP and subsequently treated with oral GS-441524 ...
Jennifer Wenk +13 more
doaj +2 more sources
High Prevalence of Multi-Viral Co-Infections and Low Rabies Seropositivity in Stray Cats of Shenzhen, China [PDF]
Stray cats (Felis vaga) are key hosts for feline and zoonotic pathogens. From June to August 2024, we conducted a cross-sectional study across six districts in Shenzhen, China, involving 126 cats sampled from three types of sites. Multiple specimens were
Tinglu Wang +9 more
doaj +2 more sources
Serology-based approach in the clinical evaluation of neonatal viral eye diseases in kittens: calicivirus, herpesvirus and panleukopenia virus [PDF]
This study aimed to examine the distribution of feline calicivirus (FCV), feline herpesvirus (FHV), and feline panleukopenia virus (FPLV), which cause neonatal feline viral diseases in kittens aged one to three months, using a Dot-ELISA bases antibody ...
Çağrı GÜLTEKİN +2 more
doaj +1 more source
An efficient method for the selective isolation of feline herpesvirus 1(FHV-1) in feline calicivirus (FCV) coinfected specimens [PDF]
Background Feline herpesvirus 1 (FHV-1) and feline calicivirus (FCV) are the most common viral pathogens of feline respiratory disease and are highly prevalent in cats worldwide.
Huanqin Zheng +11 more
doaj +2 more sources

