Results 1 to 10 of about 2,251 (170)

An efficient method for the selective isolation of feline herpesvirus 1(FHV-1) in feline calicivirus (FCV) coinfected specimens [PDF]

BMC Veterinary Research, 2023
Background Feline herpesvirus 1 (FHV-1) and feline calicivirus (FCV) are the most common viral pathogens of feline respiratory disease and are highly prevalent in cats worldwide.
Zhang Jianlong, Zhang Xingxiao
exaly   +6 more sources

Construction of Reverse Genetics System for Feline Calicivirus FCV-BJ616 and Proteomic Analysis. [PDF]

Microbiologyopen
ABSTRACT Feline calicivirus (FCV) is a primary cause of upper respiratory tract infections and oral ulcerative disease in cats and exhibits substantial genetic diversity that complicates prevention and control. In this study, we isolated the FCV‐BJ616 strain, established a reverse‐genetics system, and investigated its pathogenic ...
Xu C, Zhao J, Liu H, Gu H, Tang X, Liang L, Ding J, Hou S, Zhao X, Liang R.   +9 more
europepmc   +4 more sources

Transcriptomic analysis of Crandell-Rees feline kidney cell infections with field and vaccine feline calicivirus strains [PDF]

Virus Research
Feline upper respiratory tract disease (URTD) is a significant health concern in crowded environments, such as catteries and shelters. Feline calicivirus (FCV), which is endemic in domestic cats, is a major contributor to URTD and can cause a range of ...
Emily Kwan, Alistair R. Legione, Carol A. Hartley, Joanne M. Devlin   +3 more
doaj   +2 more sources

N-Terminal Domain of Feline Calicivirus (FCV) Proteinase-Polymerase Contributes to the Inhibition of Host Cell Transcription. [PDF]

Viruses, 2016
Feline Calicivirus (FCV) infection results in the inhibition of host protein synthesis, known as “shut-off”. However, the precise mechanism of shut-off remains unknown. Here, we found that the FCV strain 2280 proteinase-polymerase (PP) protein can suppress luciferase reporter gene expression driven by endogenous and exogenous promoters. Furthermore, we
Wu H, Zu S, Sun X, Liu Y, Tian J, Qu L.
europepmc   +5 more sources

Viral Coinfections Potentially Associated with Feline Chronic Gingivostomatitis in Cats with Feline Infectious Peritonitis [PDF]

Viruses
Feline infectious peritonitis (FIP) is a fatal but now treatable disease in cats caused by feline coronavirus (FCoV). This study prospectively investigated viral coinfections in 100 cats diagnosed with FIP and subsequently treated with oral GS-441524 ...
Jennifer Wenk, Marina L. Meli, Solène M. Meunier, Sandra Felten, Celia C. de Witt Curtius, Aline Crespo Bouzon, Ilaria Cerchiaro, Benita Pineroli, Anja Kipar, Stefan Unterer, Katharina Zwicklbauer, Katrin Hartmann, Regina Hofmann-Lehmann, Andrea M. Spiri   +13 more
doaj   +2 more sources

Comparison of the ability of feline calicivirus (FCV) vaccines to neutralise a panel of current UK FCV isolates

Journal of Feline Medicine and Surgery, 2008
Feline calicivirus (FCV) comprises a large number of strains which are related antigenically to varying degrees. The antigenic variability creates problems for choosing antigens to include in vaccines. Historically, these have been selected for use based on their cross-reactivity with a high proportion of field strains.
Alan D Radford, R M Gaskell, S Dawson
exaly   +3 more sources

Characterization of an avirulent FCV strain with a broad serum cross-neutralization profile and protection against challenge of a highly virulent vs feline calicivirus

Virus Research, 2014
Highly virulent, systemic strains of Feline calicivirus (vs FCV) have been described in recent years. These vs FCV isolates cause severe edema, cutaneous ulcers, lameness and other upper respiratory and oral clinical signs typically associated with FCV infection in cats.
David E Lowery, Vickie KING
exaly   +3 more sources

Evaluating Neutralizing Antibody Titers by Recombinant Feline Calicivirus with Heterologous Capsid Protein VP1 [PDF]

Animals
Feline calicivirus (FCV) is a major pathogen that threatens feline health worldwide. Its global prevalence, extensive genetic variability, and limited cross-protection among strains present significant challenges for vaccine development.
Yang Wang, Wei Lin, Yue Zhang, Hongling He, Yueming Wang, Saisai Li, Qiuyuan Zhang, Shile Huang, Jun Luo, Xiaofeng Guo   +9 more
doaj   +2 more sources

A novel feline herpesvirus vector subunit FCV VP1 and FPV VP2 vaccine protects cats against FHV-1 and FPV challenge and induces serum neutralizing antibody responses against FCV [PDF]

Frontiers in Immunology
Vaccines targeting feline parvovirus (FPV), feline calicivirus (FCV), and feline herpesvirus type 1 (FHV-1) are considered core vaccines and are widely recommended for feline immunoprophylaxis.
Aoxing Tang, Bo Li, Meng Zhu, Shiqiang Zhu, Da Zhang, Na Li, Miao Zhang, Yingqi Zhu, Chuanfeng Li, Chunchun Meng, Jie Zhu, Guangqing Liu   +11 more
doaj   +2 more sources

High Prevalence of Multi-Viral Co-Infections and Low Rabies Seropositivity in Stray Cats of Shenzhen, China [PDF]

Animals
Stray cats (Felis vaga) are key hosts for feline and zoonotic pathogens. From June to August 2024, we conducted a cross-sectional study across six districts in Shenzhen, China, involving 126 cats sampled from three types of sites. Multiple specimens were
Tinglu Wang, Mengmeng He, Yan Liu, Runchang Lin, Rongjie Huang, Bowen Lin, Yinyi Liang, Xiaofeng Guo, Rongqi Liu, Jun Luo   +9 more
doaj   +2 more sources