Results 121 to 130 of about 5,467,731 (352)

Transit Performance Measures in California [PDF]

open access: yes, 2016
This research is the result of a California Department of Transportation (Caltrans) request to assess the most commonly available transit performance measures in California. Caltrans wanted to understand performance measures and data used by Metropolitan
Issac, Emily, Rodier, Caroline
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Black Minds Matter: Supporting the Educational Success of Black Children in California [PDF]

open access: yes, 2015
"Black Minds Matter: Supporting the Educational Success of Black Children in California," examines how the nearly 1 million Black youth in California are faring from preschool through college and reveals the distressing disparities that newly released ...

core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

The morning after [PDF]

open access: yes
Budget - California ...
Verle Johnston
core  

Class action law suit filed by international workers against Wal-Mart, Dismissed [PDF]

open access: yes, 2009
Workers in China, Bangladesh, Indonesia, Swaziland, and Nicaragua filed a suit against Wal-Mart for its failure to monitor factories. The court concluded that Wal-Mart had no legal duty under its ‘Standards for Suppliers’ or common law negligence ...
US District Court, Central District of California
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

California Water Myths [PDF]

open access: yes, 2009
Presents eight common myths about water supply, ecosystems, and the legal and political aspects of governing California's water system and explains how each myth drives the debate, the reality, and alternatives for better informed policy ...
Ariel Dinar   +7 more
core  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

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