Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Highlights of the Foundation Center's 2001 Study: California Foundations - A Profile of the State's Grantmaking Community [PDF]
California Foundations: A Profile of the State's Grantmaking Community provides the most comprehensive analysis to date of private and community foundations in California. The report is divided into two major components.
core
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Rabbit as homeothermic species is able to keep its core body temperature within ± 1°C regulatory range. In Upper Egypt where high ambient temperature particularly at summer months, rabbit breeding ceases, by virtue of its fur, there is certain inability ...
Gehad Seddik +4 more
doaj +1 more source
Problem of Periodization and Some Aspects of the Late Work of F. Bret Hart
The article is devoted to the discussion of the problem of periodization and the study of the features of the late stage of the work of the outstanding American prose writer Francis Bret Hart (1836—1902).
A. B. Tanaseichuk, O. Yu. Osmukhina
doaj +1 more source
Planning for Complementarity: An Examination of the Roll and Opportunities of First-Tier and Second-Tier Cities Along the High-Speed Rail Network in California, Research Report 11-17 [PDF]
The coming of California High-Speed Rail (HSR) offers opportunities for positive urban transformations in both first-tier and second-tier cities. The research in this report explores the different but complementary roles that first-tier and second-tier ...
Cuff, Dana +2 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A California Without Rodenticides: Challenges for Commensal Rodent Management in the Future
Rodenticides are an essential tool in the integrated pest management of infestations of commensal rodents (Rattus norvegicus, R. rattus, and Mus musculus).
Niamh Quinn +2 more
doaj +1 more source
Abundance and distribution of California sea lions (Zalophus californianus) in central and northern California during 1998 and summer 1999 [PDF]
The abundance and distribution of California sea lions (Zalophus californianus) in central and northern California was studied to allow future evaluation of their impact on salmonids, the ecosystem, and f isheries.
Forney, Karin A., Lowry, Mark S.
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

