Results 61 to 70 of about 1,301,452 (266)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

“We Deserve the Dignity of Being Housed”: LGBTQ2+ Housing Experiences in Fresno County, California

open access: yesInternational Journal on Homelessness
Lesbian, gay, bisexual, transgender, queer, and Two-Spirit (LGBTQ2+) adults experience homelessness and housing precarity at greater rates than their cisgender and heterosexual counterparts.
Katherine Fobear
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

California leading [PDF]

open access: yesCurrent Biology, 2008
SummaryThe new environment-friendly building for the California Academy of Sciences in San Francisco is proving a huge success with staff and public alike. Nigel Williams reports.
openaire   +2 more sources

Current Distribution of the Olive Psyllid, Euphyllura olivina, in California and Initial Evaluation of the Mediterranean Parasitoid Psyllaephagus euphyllurae as a Biological Control Candidate

open access: yesInsects, 2020
The olive psyllid, Euphyllura olivina, is a newly invasive species to California with the potential to become an economical pest if it reaches the olive production regions of California’s Central Valley.
Evelyne Hougardy   +5 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Las «noticias de la provincia de Californias»: (1794), de Luis Sales

open access: yesHispania Sacra, 2002
Estudio del manuscrito de Luis de Sales sobre Noticias de la Provincia de California, que analiza los primeros veinte años de los dominicos en California.
Alfonso Esponera Cerdán
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

First Report of Root-Knot Nematode, Meloidogyne incognita, on Tree Houseleek (Aeonium arboreum) in the United States

open access: yesJournal of Nematology
Aeonium, or tree houseleek (Aeonium arboreum), is a bushy, perennial succulent and a popular ornamental plant in regions such as California, New Zealand, Australia, Sicily, Gibraltar, and Chile.
Baniya Anil   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

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