Results 61 to 70 of about 1,692,259 (260)
Journal of English Studies, 2013 Blended learning at universities has emerged as a solution to address the need of fostering students’ independent and life-long learning as well as foreign language acquisition. The methodology combines on-campus and on-line tuition.
M. Teresa Martín de Lama
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 2017 Background: 'Call' is a 40-minute solo live performance presented in the international 'Performing, Writing' program directed by Julieanna Preston. It was presented to the public at Bats Theatre, Wellington's home of independent theatre as part of The ...
Mick Douglas (18044032)
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Наукові записки НаУКМА. Комп'ютерні науки, 2020 The goal of this work is to practically apply methods of empirical engineering software, algorithms for data collection and data analysis. The results include software measurement, analysis and selection of direct and indirect metrics for research and ...
Andrii Hlybovets, Oleksandr Shapoval
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2015 This edition of the CALL Insider includes descriptions of recent CALL activities, updates from training centers, and other CALL-related ...
Center for Army Lessons Learned
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Use of personal call alarms among community-dwelling older people. [PDF]
, 2012 Having a fall and then lying on the floor for an hour or more is known as a ‘long lie’, which are associated with serious injury and an elevated risk of admission to hospital, long-term care, and death.
Victor, C.R. +3 more
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