Results 81 to 90 of about 358,887 (259)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A Dynamic Allocation Method on Virtual Resource in Cloud Call Center
Dianxin kexue, 2013 Business platform built on cloud computing cloud resource pool call center system, can not only do load balancing control at the operational level, realize intelligent call center scheduling and resource allocation, automatically do the equalization ...
Ying Ling, Wei Xu
doaj +2 more sources
Revista de Ciências da Administração : RCA, 2010 Esta pesquisa teve como objetivo principal analisar o impacto da reestruturação organizacional ocorrida em uma empresa de telefonia celular na identidade dos funcionários.
Daniela Cristina Soares, Adriane Vieira
doaj
Noise at Workplaces in the Call Center
Archives of Acoustics, 2010 AbstractIn the last years the number of new forms of workplaces, such as call centers, increases. It is defined as a workstation where the basic tasks of a worker are carried out with the use of a phone and a computer. According to statistics, about 1.3-4% of workers are employed in call centers in the European countries.
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Research and Design of Distributed Parallel Processing Cloud CTI System Architecture
Dianxin kexue, 2015 CTI is responsible for the agent registration management，scheduling management in call center.Therefore，the CTI system’s stability and performance of the integrated call center platform，the scale of the robustness of the agents will have a direct impact ...
Qing Li, Wenhong Zhou
doaj +2 more sources