Results 61 to 70 of about 356,160 (259)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FACES, 2018 Se presenta una investigación descriptiva transversal que tiene como objetivo evaluar niveles de burnout y engagement en teleoperadores de un call center de la ciudad de Mar del Plata, Argentina.
Yamila Fernanda Silva Peralta +3 more
doaj
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Announcing Delay Information to Improve Service in a Call Center With Repeat Customers
IEEE Access, 2019 We study the model of predicting and announcing delays, including customer satisfaction and repeat the behavior. In a call center, anticipated delays affect the customer behaviors of balking and reneging; we characterize the level of satisfaction with ...
Miao Yu +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
La guerra silenciosa en el mundo de los Call Centers [PDF]
Papeles del CEIC: International Journal on Collective Identity Research, 2012 El objetivo de este artículo es indagar la operatoria del miedo como mecanismo social a partir del análisis del conflicto emergente en el sector de Call Centers de la ciudad de Córdoba, Argentina.
Pedro Lisdero
doaj
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
“Call Center” sebagai Alat Komunikasi Pemasaran di Abad ke-21
MediaTor, 2007 Call center is a part of contact center who responsible to serve customers. Call center relates corporate and targeted market. As communication media whose tasks are focused to serve the customers, call center receives and processes consumer expectations
Ratih Tresnati
doaj
Auditory fatigue among call dispatchers working with headsets
International Journal of Occupational Medicine and Environmental Health, 2018 Objectives To determine whether call center dispatchers wearing headsets are subject to auditory fatigue at the end of a work shift. Material and Methods Data was gathered at times when call centers were busiest. All call operators wore a headset for up
Thomas Venet +8 more
doaj +1 more source