Results 111 to 120 of about 384,773 (212)

Caloric restriction causes symmetric cell division and delays aging in Escherichia coli [PDF]

, 2008
Aging is one of the most intriguing processes of biology and despite decades of research, many aspects of aging are poorly understood. Aging is known to occur in bacteria and yeast that divide with morphological asymmetry.
Milind G. Watve, Snehal Bari, Uttara Lele, Samit Watve, Prajakta Belsare, Sarika Karande   +5 more
core  

Caloric Restriction Timecourse Project

Study investigating if the metabolic and skeletal effects of caloric restriction, in mice, depend on the duration of caloric ...
William Peter Cawthorn
core   +2 more sources

A discovery platform for the identification of caloric restriction mimetics with broad health-improving effects. [PDF]

Autophagy, 2020
Kepp O, Chen G, Carmona-Gutierrez D, Madeo F, Kroemer G.   +4 more
europepmc   +1 more source

Effect of caloric restriction in DKO mice.

, 2017
Effect of caloric restriction in DKO mice.
Maarten Vanhaverbeke (3697519), Benjamine Geeraert (187732), Maarten Hulsmans (181118), Dieuwke De Keyzer (187734), Stefan Janssens (390984), Paul Holvoet (122610)   +5 more
core   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

A biomechanical optimized Zr58Cu25Al14Nb3 bulk metallic glass dental implant improves peri‐implant stress distribution and bone quality under physiological loading

BMEMat, EarlyView.
This study reports a novel Zr58Cu25Al14Nb3 bulk metallic glass that possesses high mechanical strength and low elastic modulus, which further promotes efficient mechanotransduction and significantly improves peri‐implant bone quality upon cyclic occlusal loading.
Yunshu Wu, Feifei Wang, Yuan He, Yaopeng Zhang, Yuhao Zeng, Fu Zheng, Zhanqi Wei, Sukun Tian, Kinon Chen, Baoan Sun, Yuchun Sun   +10 more
wiley   +1 more source

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

BMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue, Xiaoyu Zhao, Yuqian Wang, Lijin Shi, Qi Shuai   +4 more
wiley   +1 more source

Caloric restriction, SIRT1 and longevity

More than 70 years after its initial report, caloric restriction stands strong as the most consistent non- pharmacological intervention increasing lifespan and protecting against metabolic disease.
Cantó, C, Auwerx, J
core   +1 more source

Exosome‐mimetic vesicle‐encapsulated multi‐responsive antibacterial hydrogel core‐shell microneedle patch promotes scarless healing of infected wounds

BMEMat, EarlyView.
The core‐shell microneedle patch VP@FNV‐CuO2‐MN was fabricated by encapsulating n‐CuO2 in a moderately crosslinked PVA/CMCS/Borax4 hydrogel shell and VP‐loaded fibroblast membrane nanovesicles (VP@FNV) in a highly crosslinked PVA/CMCS/Borax6 hydrogel core. Upon application to an infected wound, the acidic microenvironment triggers Fenton‐like reactions
Ziwei Jiang, Huihui Zhang, Lianglong Chen, Zhangfeifan Yang, Sai Cao, Yufang He, Xiaoyang Liu, Siew Yee Wong, Xu Li, Hai Zhou, Ziyan Li, Zijun Zheng, Lei Yang   +12 more
wiley   +1 more source