Results 41 to 50 of about 2,921,086 (312)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Clinical diagnoses of patients showing caloric inversion

open access: yesBrazilian Journal of Otorhinolaryngology
Objectives: When air irrigation is used for caloric stimulation in patients with a perforated ear, warm irrigation may elicit a nystagmus that initially beats in the opposite direction of what is expected for warm irrigations, which is referred to as ...
Hansol Kim   +4 more
doaj   +1 more source

PSYNDEX Tests Review für ST-SM - Sporttest: Sportmotorische Tests für Mädchen

open access: yes, 1986
This is a PSYNDEX Tests Review of ST-SM - Sporttest: Sportmotorische Tests für Mädchen. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Waschler, Gerhard
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Comparative utility of vestibular function tests in patients with peripheral and central vestibular dysfunction

open access: yesJournal of Otology
Background: Bithermal caloric irrigation, video head impulse test (vHIT), and rotational testing are commonly used to assess peripheral vestibular function, but the relative clinical utility of each test in differentiating patients with peripheral ...
Cameron B. Fattahi   +4 more
doaj   +1 more source

The effect of cochlear implant surgery on vestibular function in adults: A meta-analysis study

open access: yesFrontiers in Neurology, 2022
IssueThe findings in literature indicate inconsistency in the complications caused by the implant of electrodes in the cochlea; vestibular alterations and balance disorders are mentioned as the most likely.PurposeTo evaluate, in literature, through the ...
Fabiane de Castro Vaz   +10 more
doaj   +1 more source

PSYNDEX Tests Review für LKT 5-6 - Lesekompetenz-Tests

open access: yes, 2006
This is a PSYNDEX Tests Review of LKT 5-6 - Lesekompetenz-Tests. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Mayer, Anne-Kathrin
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Audio-vestibular and radiological analysis in Meniere’s disease

open access: yesBrazilian Journal of Otorhinolaryngology, 2022
Objective: Intravenous gadolinium-enhanced inner ear magnetic resonance imaging (IV Gd-enhanced inner ear MRI) is a new technique for diagnosing Meniere’s disease (MD).
Arzu Kirbac   +5 more
doaj   +1 more source

PSYNDEX Tests Review für FAT - Flugangst-Tests

open access: yes, 1997
This is a PSYNDEX Tests Review of FAT - Flugangst-Tests. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Weiderer, Monika
core   +1 more source

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