Results 41 to 50 of about 109,301 (302)

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

The effect of cochlear implant surgery on vestibular function in adults: A meta-analysis study

Frontiers in Neurology, 2022
IssueThe findings in literature indicate inconsistency in the complications caused by the implant of electrodes in the cochlea; vestibular alterations and balance disorders are mentioned as the most likely.PurposeTo evaluate, in literature, through the ...
Fabiane de Castro Vaz, Fabiane de Castro Vaz, Leonardo Petrus, Wagner Rodrigues Martins, Wagner Rodrigues Martins, Isabella Monteiro de Castro Silva, Jade Arielly Oliveira Lima, Jade Arielly Oliveira Lima, Nycolle Margarida da Silva Santos, Natália Turri-Silva, Fayez Bahmad   +10 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Audio-vestibular and radiological analysis in Meniere’s disease

Brazilian Journal of Otorhinolaryngology, 2022
Objective: Intravenous gadolinium-enhanced inner ear magnetic resonance imaging (IV Gd-enhanced inner ear MRI) is a new technique for diagnosing Meniere’s disease (MD).
Arzu Kirbac, Saziye Armagan Incesulu, Ugur Toprak, Hamdı Caklı, Hulya Ozen, Suzan Saylisoy   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Comparative utility of vestibular function tests in patients with peripheral and central vestibular dysfunction

Journal of Otology
Background: Bithermal caloric irrigation, video head impulse test (vHIT), and rotational testing are commonly used to assess peripheral vestibular function, but the relative clinical utility of each test in differentiating patients with peripheral ...
Cameron B. Fattahi, Christopher Zaro, Janice J. Chung, Richard F. Lewis, Divya A. Chari   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Insights Into Responses to Caloric and Head Impulse Stimulation in Lateral Semicircular Canal Benign Paroxysmal Positional Vertigo [PDF]

Clinical and Experimental Otorhinolaryngology
Objectives. The aim of this study was to investigate the pathophysiology of persistent geotropic direction-changing positional nystagmus (pGeo DCPN) by analyzing caloric responses and the clinical course in patients with pGeo DCPN and other variants of ...
Seong Hoon Bae, Sang Hyun Kwak, Jeon Mi Lee, Ji Hyuk Han, Dae Bo Shim, Sung Huhn Kim   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source