Results 51 to 60 of about 109,301 (302)

Dietary adherence to whole grain and refined grain rich diets in a randomized controlled trial [PDF]

, 2016
Dietary adherence is the degree to which participants follow prescribed dietary protocol. Without measuring adherence, it is not possible to validly measure the effect of the intervention.
Palladino, Joel
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A Question of Food Intake: The Impact of Living Arrangement and Meal Factors on Total Daily Caloric Intake [PDF]

, 2017
There has been dramatic weight gain among college students during their collegiate years. A food diary can give much insight of a college student’s life.
Sorenson, Kalei
core   +1 more source

Mice that gorged during dietary restriction increased foraging related behaviors and differed in their macronutrient preference when released from restriction [PDF]

, 2015
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed ...
Hambly, Catherine, Speakman, John R
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Subjective Visual Vertical and Horizontal Abnormalities in a Patient with Lateral Medullary Syndrome-A Case Report [PDF]

Iranian Journal of Otorhinolaryngology, 2015
Introduction: Evaluation of persistent vertigo in post infarct patients is very important as the management depends on whether the cause is purely of central origin or due to associated vestibular affliction.
Amit Tyagi, Gaurav Ashish, Anjali Lepcha, Achamma Balraj   +3 more
doaj   +2 more sources

Clinical characteristics of patients with dizziness/vertigo showing a dissociation between caloric and video head impulse test results

Ear, Nose & Throat Journal
Objective To explore the clinical characteristics of patients with dizziness/vertigo who showed a dissociation between the results of the caloric test and video head impulse test (vHIT). Methods A total of 327 patients who complained of dizziness/vertigo
Xiang Li MD, Xia Ling PhD, Zheyuan Li PhD, Ning Song MD, Xiahong Ba MD, Bo Yang MD, Xu Yang MD, Rubo Sui PhD   +7 more
doaj   +1 more source

AMP-activated kinase and the endogenous endocannabinoid system might contribute to antinociceptive effects of prolonged moderate caloric restriction in mice

Molecular Pain, 2017
Background Caloric restriction is associated with broad therapeutic potential in various diseases and an increase in health and life span. In this study, we assessed the impact of caloric restriction on acute and inflammatory nociception in mice, which ...
Tanya S King-Himmelreich, Christine V Möser, Miriam C Wolters, Julia Schmetzer, Moritz Möller, Yannik Schreiber, Nerea Ferreirós, Gerd Geisslinger, Ellen Niederberger   +8 more
doaj   +1 more source

Caloric vestibular stimulation in aphasic syndrome [PDF]

, 2013
Caloric vestibular stimulation (CVS) is commonly used to diagnose brainstem disorder but its therapeutic application is much less established.
Milberg, William P., Morris, Rachael, Sakel, Mohamed, Wilkinson, David T.   +3 more
core   +3 more sources