Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu +6 more
wiley +1 more source
A high-calorie diet exacerbates lipopolysaccharide-induced pneumonia by promoting acetate-mediated macrophage polarization via the HDAC9/10-HIF-1α-glycolysis axis. [PDF]
Li Q +7 more
europepmc +1 more source
Move beyond free radical theory of aging
Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley +1 more source
Causal Relationships Between Popular Diets (Low-Calorie, Vegetarian, and Gluten-Free Diets) and Inflammatory Skin Diseases: A Mendelian Randomization Study. [PDF]
Yu Y +6 more
europepmc +1 more source
Calorie Restriction as a Risk Factor for Cardiovascular Disease in the Aged Population
Ifeoluwa Claudius Daramola +7 more
openalex +1 more source
ABSTRACT Aspartame and acesulfame‐K are commonly used non‐nutritive artificial sweeteners, but their impacts on cardiovascular disease and metabolic dysfunction‐associated fatty liver disease (MASLD) are unclear. In this study, we evaluated the impacts of aspartame and acesulfame‐K on MASLD and atherosclerosis in male Ldlr−/− mice fed an AMLN diet ...
Jingjing Xu +3 more
wiley +1 more source
Urinary signatures are associated with calorie restriction-mediated weight loss in obese Diversity Outbred mice. [PDF]
Paules EM +13 more
europepmc +1 more source
ABSTRACT Purpose The prevalence of food insecurity (FI) and its associated outcomes among undergraduate students have been widely researched, however studies focusing on FI among professional students are limited. This study investigated the associations between FI, sleep‐related variables, and stress among dental students from predominantly Black and ...
Brian Laurence +6 more
wiley +1 more source
Exercise maintains LEAP2 levels after weight loss in females with obesity. [PDF]
Holt J +15 more
europepmc +1 more source

