Results 21 to 30 of about 34,470 (288)
Calorie Restriction— the SIR2 Connection [PDF]
Cell, 2005 A nutritious diet low in calories improves the health and extends the life span of rodents. Recent studies identified a gene, SIR2, which encodes an NAD-dependent deacetylase and may mediate the effects of calorie restriction. In this review, we discuss SIR2 genes and calorie restriction in the lower organisms yeast and Drosophila. We then describe the
Guarente, Leonard, Picard, Frédéric
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NRF2, cancer and calorie restriction [PDF]
Oncogene, 2010 The transcription factor NF-E2-related factor (NRF2) is a key regulator of several enzymatic pathways, including cytoprotective enzymes in highly metabolic organs. In this review, we summarize the ongoing research related to NRF2 activity in cancer development, focusing on in vivo studies using NRF2 knockout (KO) mice, which have helped in defining the
Martín-Montalvo, Alejandro +3 more
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The effect of continuous training and caloric restriction on isoprostane 8, malondialdehyde and interleukin-6 in obese male rats [PDF]
ورزش و علوم زیست حرکتیIntroduction and Purpose: Obesity-induced inflammation affects various body systems. This study aimed to examine the effects of continuous exercise and calorie restriction on 8-isoprostane, malondialdehyde (MDA), and interleukin-6 (IL-6) in obese male ...
hossien amiri +4 more
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Artemisinin mimics calorie restriction to trigger mitochondrial biogenesis and compromise telomere shortening in mice [PDF]
PeerJ, 2015 Calorie restriction is known to extend lifespan among organisms by a debating mechanism underlying nitric oxide-driven mitochondrial biogenesis. We report here that nitric oxide generators including artemisinin, sodium nitroprusside, and L-arginine ...
Da-Ting Wang +5 more
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Aging, Calorie Restriction and Calorie Restriction Mimetics
Rad Hrvatske akademije znanosti i umjetnosti. Medicinske znanosti, 2019 ABSTRACR: In line with the increase in the number of older people in the world, the focus of scientists is directed at examining mechanisms of the aging process as well as establishing strategies/interventions in order to slow down aging and achieve longevity.
Čepelak, Ivana +2 more
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Does calorie restriction improve cognition?
IBRO Reports, 2020 Calorie restriction (CR) has been considered the most effective non-pharmacological intervention to counteract aging-related diseases and improve longevity. This intervention has shown beneficial effects in the prevention and treatment of several chronic
Isabella Rocha Dias +6 more
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Kuwait Journal of Science, 2022 This study aims to analyze the effect of the combination of intermittent calorie restriction and moderate intensity interval training (MIIT) on serum CRP levels as one of inflamatory mediator and blood glucose levels in female mice exposed to a high ...
Muchammad Rif'at Fawaid As'ad +3 more
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Cells, 2022 Calorie restriction enhances stem cell self-renewal in various tissues, including the mammary gland. We hypothesized that similar to their intestinal counterparts, mammary epithelial stem cells are insulated from sensing changes in energy supply ...
Anna Kosenko +3 more
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Effects of high glucose, egg yolk intake, calorie restriction, and air pollution on rats’ fat cell
JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2023 Background: Obesity is one of the cardiovascular disease risk factors that cause hypertrophy or hyperplasia of adipocytes. Changes in fat cells have the potential to increase inflammation and insulin resistance.
Diniwati Mukhtar +6 more
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Metabolic adaptation to calorie restriction
Science Signaling, 2020 Metabolites that may enable calorie restriction to induce hypothermia and extend health span are identified.
Carlos Guijas +10 more
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