Results 11 to 20 of about 21,405 (217)
Hepatology, EarlyView., 2022 In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole +12 more
wiley +1 more source
Calprotectin in Cystic Fibrosis [PDF]
BMC Pediatrics, 2014 There is increasing evidence that intestinal inflammation plays a major role in gastrointestinal symptoms in cystic fibrosis (CF). Fecal calprotectin is a marker that is elevated in several gastrointestinal inflammatory diseases, but little is known about its value in CF.
Rumman, Nisreen +6 more
openaire +2 more sources
Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein
Frontiers in Immunology, 2022 Increased neutrophils and elevated level of circulating calprotectin are hallmarks of severe COVID-19 and they contribute to the dysregulated immune responses and cytokine storm in susceptible patients.
Jia Tong Loh +4 more
doaj +1 more source
Calprotectin in rheumatic diseases [PDF]
Experimental Biology and Medicine, 2016 Calprotectin is a heterodimer formed by two proteins, S100A8 and S100A9, which are mainly produced by activated monocytes and neutrophils in the circulation and in inflamed tissues. The implication of calprotectin in the inflammatory process has already been demonstrated, but its role in the pathogenesis, diagnosis, and monitoring of rheumatic diseases
OMETTO, FRANCESCA +6 more
openaire +2 more sources
F1000Research, 2023 Background Despite significant advances in neonatal care, neonatal sepsis remains a major contributor to mortality, morbidity, and protracted hospitalization. The development of early possible diagnostic indicators for newborn sepsis is critical.
Vaman Kulkarni +5 more
doaj +1 more source
The role of calprotectin in rheumatoid arthritis [PDF]
Journal of Translational Internal Medicine, 2019 Abstract Rheumatoid arthritis (RA) is an inflammatory autoimmune disease characterized by inflammatory cell infiltration, high levels of cytokines, and erosion of cartilage and bone in joints. Calprotectin (CLP), as a recently described member of S100 family proteins, is a heterodimeric complex of S100A8 and S100A9.
Wang, Qin, Chen, Weiqian, Lin, Jin
openaire +2 more sources
The effect of calprotectin on TSLP and IL-25 production from airway epithelial cells
Allergology International, 2017 Background: Calprotectin is a heterodimer complex of the S100A8 and S100A9 proteins, and has various functions as an innate mediator at the sites of inflammation.
Tomohisa Kato +4 more
doaj +1 more source
The Role of Calprotectin in Pediatric Disease [PDF]
BioMed Research International, 2013 Calprotectin (CP) is a calcium- and zinc-binding protein of the S100 family expressed mainly by neutrophils with important extracellular activity. The aim of the current review is to summarize the latest findings concerning the role of CP in a diverse range of inflammatory and noninflammatory conditions among children.
George Vaos +3 more
openaire +3 more sources
mBio, 2020 Nutritional immunity is an elegant host mechanism used to starve invading pathogens of necessary nutrient metals. Calprotectin, a metal-binding protein, is produced abundantly by neutrophils and is found in high concentrations within inflammatory sites ...
Lindsey R. Burcham +12 more
doaj +1 more source
Supporting the diagnosis of infantile colic by a point of care measurement of fecal calprotectin
Frontiers in Pediatrics, 2022 BackgroundInfantile colic (IC) is a condition characterized by extensive crying which affects about 20% of all infants during their first months of life.
Henning Sommermeyer +4 more
doaj +1 more source