Results 251 to 260 of about 28,252 (277)

Calreticulin mutations in myeloproliferative neoplasms

2021
Calreticulin (CALR) is a chaperone present in the endoplasmic reticulum, which is involved in the quality control of N-glycosylated proteins and storage of calcium ions. In 2013, the C-terminal mutation in CALR was identified in half of the patients with essential thrombocythemia and primary myelofibrosis who did not have a JAK2 or MPL mutation.
openaire   +2 more sources

Ecto‐calreticulin in immunogenic chemotherapy

Immunological Reviews, 2007
Summary:The conventional treatment of cancer relies upon radiotherapy and chemotherapy. Such treatments supposedly mediate their effects via the direct elimination of tumor cells. Nonetheless, there are circumstances in which conventional anti‐cancer therapy can induce a modality of cellular demise that elicits innate and cognate immune responses ...
Michel, Obeid, Antoine, Tesniere, Theocharis, Panaretakis, Roberta, Tufi, Nick, Joza, Peter, van Endert, François, Ghiringhelli, Lionel, Apetoh, Nathalie, Chaput, Caroline, Flament, Evelyn, Ullrich, Stéphane, de Botton, Laurence, Zitvogel, Guido, Kroemer   +13 more
openaire   +2 more sources

Mammalian calreticulin

1997
Abstract The calreticulin cDNA sequence (GenBank accession numbers M84739, human; X53363, rat; L13462, bovine) predicts a soluble protein of c. 400 amino acids, with an N-terminal signal sequence, C-terminal tetrapeptide KDEL ER retrieval signal (Michalak etal., 1992).
openaire   +1 more source

Calreticulin

2016
Elzbieta Dudek, Marek Michalak
  +4 more sources

Calreticulin

2008
  +4 more sources

Immunosuppression by Mutated Calreticulin Released from Malignant Cells

Molecular Cell, 2020
Liwei Zhao, Wei Xie, CARLOS Lopez-Otin   +2 more
exaly  

Calreticulin in the immune system: ins and outs

Trends in Immunology, 2013
Malini Raghavan, Sanjeeva J Wijeyesakere   +1 more
exaly  

Calreticulin and calnexin in the endoplasmic reticulum are important for phagocytosis

EMBO Journal, 2001
Andrei N Lupaş, Mary Ecke, GÜNTHER Gerisch   +2 more
exaly  

Calreticulin: not just another calcium-binding protein

Molecular and Cellular Biochemistry, 1994
Marek Michalak, Opas Michal, Michalak Marek   +2 more
exaly  

Calreticulin

2011
openaire   +2 more sources