Results 1 to 10 of about 2,783 (65)
Biomarkers of Radiotherapy-Induced Immunogenic Cell Death
Cells, 2021 Radiation therapy (RT) can induce an immunogenic variant of regulated cell death that can initiate clinically relevant tumor-targeting immune responses.
Rianne D. W. Vaes +3 more
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Immunogenic Cell Death Induction by Ionizing Radiation
Frontiers in Immunology, 2021 Immunogenic cell death (ICD) is a form of regulated cell death (RCD) induced by various stresses and produces antitumor immunity via damage-associated molecular patterns (DAMPs) release or exposure, mainly including high mobility group box 1 (HMGB1 ...
Mengqin Zhu +17 more
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Cells, 2022 Innovative strategies to re-establish the immune-mediated destruction of malignant cells is paramount to the success of anti-cancer therapy. Accumulating evidence suggests that radiotherapy and select chemotherapeutic drugs and small molecule inhibitors ...
Kellsye P. Fabian +3 more
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Nanocarrier-Mediated Immunogenic Cell Death for Melanoma Treatment
International Journal of Nanomedicine, 2023 Jiandong Wang,1– 3,* Jinyuan Ma,1,4,* Zongguang Tai,1,4,* Lisha Li,1,4 Tingrui Zhang,1,4 Tingting Cheng,1– 3 Junxia Yu,1– 3 Quangang Zhu,1,4 Leilei Bao,2 Zhongjian Chen1,4 1Shanghai Skin Disease Hospital, School of Medicine, Tongji University,
Wang J +9 more
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Immunogenic Cell Death and Immunotherapy of Multiple Myeloma
Frontiers in Cell and Developmental Biology, 2019 Over the past decades, immunotherapy has demonstrated a prominent clinical efficacy in a wide variety of human tumors. For many years, apoptosis has been considered a non-immunogenic or tolerogenic process whereas necrosis or necroptosis has long been ...
Alfonso Serrano-del Valle +3 more
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Frontiers in Oncology, 2021 Cancer treatment has rapidly entered the age of immunotherapy, and it is becoming clear that the effective therapy of established tumors necessitates rational multi-combination immunotherapy strategies.
Kellsye P. Fabian +2 more
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Immunogenic Cell Death-Based Cancer Vaccines
Frontiers in Immunology, 2021 Cancer immunotherapy has achieved great advancement in the past decades. Whereas, its response is largely limited in immunologically cold tumors, in an urgent need to be solve.
Ming-Zhu Jin, Xi-Peng Wang
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Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells. [PDF]
PLoS ONE, 2013 Durable tumor cell eradication by chemotherapy is challenged by the development of multidrug-resistance (MDR) and the failure to induce immunogenic cell death.
Chiara Riganti +8 more
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Scientific Reports, 2023 Previous studies have shown the potential of immunogenic cell death-related modalities in myeloma. The significance of IL5RA in myeloma and immunogenic cell death remains unknown.
Cong Xu +3 more
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Ferroptosis: friend or foe in cancer immunotherapy?
OncoImmunology, 2023 Ferroptosis has gained interest due to it immunogenicity and the higher sensitivity of cancer cells to it. However, it was recently shown that ferroptosis in tumor-associated neutrophils leads to immunosuppression and negatively impacts therapy. Here, we
Robin Demuynck +3 more
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