Results 1 to 10 of about 7,237,819 (287)
Biomarkers of Radiotherapy-Induced Immunogenic Cell Death [PDF]
Cells, 2021 Radiation therapy (RT) can induce an immunogenic variant of regulated cell death that can initiate clinically relevant tumor-targeting immune responses.
Rianne D. W. Vaes +3 more
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Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells. [PDF]
PLoS ONE, 2013 Durable tumor cell eradication by chemotherapy is challenged by the development of multidrug-resistance (MDR) and the failure to induce immunogenic cell death.
Chiara Riganti +8 more
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Scientific Reports, 2023 Previous studies have shown the potential of immunogenic cell death-related modalities in myeloma. The significance of IL5RA in myeloma and immunogenic cell death remains unknown.
Cong Xu +3 more
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Tumor-intrinsic determinants of immunogenic cell death modalities
OncoImmunology, 2021 The immune system can recognize tumor cells to mount antigen-specific T cell response. Central to the establishment of T cell-mediated adaptive immunity are the inflammatory events that facilitate antigen presentation by stimulating the expression of MHC
Samuel T Workenhe +2 more
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Immunogenic Cell Death-Based Cancer Vaccines [PDF]
Frontiers in Immunology, 2021 Cancer immunotherapy has achieved great advancement in the past decades. Whereas, its response is largely limited in immunologically cold tumors, in an urgent need to be solve.
Ming-Zhu Jin, Xi-Peng Wang
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Immunogenic Cell Death Induction by Ionizing Radiation [PDF]
Frontiers in Immunology, 2021 Immunogenic cell death (ICD) is a form of regulated cell death (RCD) induced by various stresses and produces antitumor immunity via damage-associated molecular patterns (DAMPs) release or exposure, mainly including high mobility group box 1 (HMGB1 ...
Mengqin Zhu +17 more
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Dynamical Boolean Modeling of Immunogenic Cell Death [PDF]
Frontiers in Physiology, 2020 As opposed to the standard tolerogenic apoptosis, immunogenic cell death (ICD) constitutes a type of cellular demise that elicits an adaptive immune response.
Andrea Checcoli +20 more
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Frontiers in Oncology, 2021 Cancer treatment has rapidly entered the age of immunotherapy, and it is becoming clear that the effective therapy of established tumors necessitates rational multi-combination immunotherapy strategies.
Kellsye P. Fabian +2 more
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Ferroptosis: friend or foe in cancer immunotherapy?
OncoImmunology, 2023 Ferroptosis has gained interest due to it immunogenicity and the higher sensitivity of cancer cells to it. However, it was recently shown that ferroptosis in tumor-associated neutrophils leads to immunosuppression and negatively impacts therapy. Here, we
Robin Demuynck +3 more
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Frontiers in Oncology, 2021 Necroptosis is a form of programmed cell death (PCD) characterized by RIP3 mediated MLKL activation and increased membrane permeability via MLKL oligomerization.
Jia-long Qi +7 more
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