Results 41 to 50 of about 6,745,376 (244)

Alternative cell death pathways and cell metabolism [PDF]

, 2013
While necroptosis has for long been viewed as an accidental mode of cell death triggered by physical or chemical damage, it has become clear over the last years that necroptosis can also represent a programmed form of cell death in mammalian cells.
Simone Fulda, Fulda, Simone
core   +1 more source

Laser nanobubbles induce immunogenic cell death in breast cancer [PDF]

, 2021
Recent advances in immunotherapy have highlighted a need for therapeutics that initiate immunogenic cell death in tumors to stimulate the body's immune response to cancer.
Milner, Thomas E, Feng, Xu, Tunnell, James W, Baker, Aaron B, Suggs, Laura J, Widman, Jessica A, Katta, Nitesh, Betancourt, Tania, Takematsu, Eri, Nguyen, Hieu TM, Torres-Hurtado, Susana A   +10 more
core   +1 more source

Nanotechnology-Assisted Immunogenic Cell Death for Effective Cancer Immunotherapy

Vaccines, 2023
Tumor vaccines have been used to treat cancer. How to efficiently induce tumor-associated antigens (TAAs) secretion with host immune system activation is a key issue in achieving high antitumor immunity. Immunogenic cell death (ICD) is a process in which
Yichen Guo, Rong Ma, Mengzhe Zhang, Yongjian Cao, Zhenzhong Zhang, Weijing Yang   +5 more
doaj   +1 more source

Immunogenic cell death: The cornerstone of oncolytic viro-immunotherapy

Frontiers in Immunology, 2023
According to the World Health Organization, cancer is one of the leading global health concerns, causing nearly 10 million deaths in 2020. While classical chemotherapeutics produce strong cytotoxicity on cancer cells, they carry limitations of drug ...
Lalitha Palanivelu, Ching-Hsuan Liu, Ching-Hsuan Liu, Ching-Hsuan Liu, Liang-Tzung Lin, Liang-Tzung Lin   +5 more
doaj   +1 more source

The Concept of Immunogenic Cell Death in Antitumor Immunity [PDF]

Klinicka onkologie, 2015
Cancer cell death can be immunogenic or nonimmunogenic depending on the initiating stimulus. The immunogenic characteristics of immunogenic cell death are mainly mediated by damage-associated molecular patterns represented by preapoptotic exposure of calreticulin and heat shock proteins (HSP70 and HSP90) from endoplasmic reticulum at the cell surface ...
J, Fučíková, J, Bartůňková, R, Špíšek   +2 more
openaire   +2 more sources

The anticancer peptide RT53 induces immunogenic cell death. [PDF]

PLoS ONE, 2018
In recent years, immunogenic cell death (ICD) has emerged as a revolutionary concept in the development of novel anticancer therapies. This particular form of cell death is able, through the spatiotemporally defined emission of danger signals by the ...
Ewa Pasquereau-Kotula, Justine Habault, Guido Kroemer, Jean-Luc Poyet   +3 more
doaj   +1 more source

Trial watch: chemotherapy-induced immunogenic cell death in oncology

OncoImmunology, 2023
Immunogenic cell death (ICD) refers to an immunologically distinct process of regulated cell death that activates, rather than suppresses, innate and adaptive immune responses. Such responses culminate into T cell-driven immunity against antigens derived
Jenny Sprooten, Raquel S. Laureano, Isaure Vanmeerbeek, Jannes Govaerts, Stefan Naulaerts, Daniel M. Borras, Lisa Kinget, Jitka Fucíková, Radek Špíšek, Lenka Palová Jelínková, Oliver Kepp, Guido Kroemer, Dmitri V. Krysko, An Coosemans, Rianne D.W. Vaes, Dirk De Ruysscher, Steven De Vleeschouwer, Els Wauters, Evelien Smits, Sabine Tejpar, Benoit Beuselinck, Sigrid Hatse, Hans Wildiers, Paul M. Clement, Peter Vandenabeele, Laurence Zitvogel, Abhishek D. Garg   +26 more
doaj   +1 more source

Peptide Aggregation Induced Immunogenic Cell Death

, 2022
Cell death is an inevitable biological outcome, every living thing dies. However, how cells die is an important question and ultimately is decisive in homeostasis and disease progression.
Gunay, Gokhan
core  

A Functional Assay to Determine the Capacity of Oncolytic Viruses to Induce Immunogenic Tumor Cell Death

, 2020
International audienceOncolytic immunotherapy efficacy relies partially on the induction of immunogenic tumor cell death following infection with oncolytic viruses (OV) to induce an antitumor immune response. Here, we describe a method to determine if an
Delaunay, Tiphaine, Tangy, Frédéric, Gregoire, Marc, Boisgerault, Nicolas, Achard, Carole, Fonteneau, Jean-François   +5 more
core   +1 more source

Cell arrest and cell death in mammalian preimplantation development [PDF]

, 2011
The causes, modes, biological role and prospective significance of cell death in preimplantation development in humans and other mammals are still poorly understood.
Tuna Güngör, Eckhard Wolf, Güngör Tuna, Horst-Dieter Reichenbach, Leidenfrost, Sandra, Reichenbach, Myriam, Reichenbach Myriam, Leidenfrost Sandra, Reichenbach, Horst-Dieter, Myriam Reichenbach, Sandra Leidenfrost, Marc Boelhauve, Fred Sinowatz, Habermann, Felix A., Felix A Habermann, Wolf Eckhard, Felix A. Habermann, Boelhauve, Marc, Güngör, Tuna, Boelhauve Marc, Wolf, Eckhard, Sinowatz, Fred, Reichenbach Horst-Dieter, Sinowatz Fred, Habermann Felix A.   +24 more
core   +2 more sources