Results 11 to 20 of about 6,745,376 (244)

Radiotherapy and Immunogenic Cell Death [PDF]

Seminars in Radiation Oncology, 2015
Advances in understanding the mechanisms that underlie the interplay between radiation-invoked immune responses and tumor regression are underway. Emerging applications of local radiotherapy as an immunologic adjuvant have provided radiation oncologists ...
Lionel Apetoh, Encouse B. Golden, Apetoh, Lionel, Golden, Encouse B.   +3 more
core   +3 more sources

Immunogenic cell death [PDF]

The International Journal of Developmental Biology, 2015
Currently, it is widely acknowledged that a proactive anticancer immunosurveillance mechanism takes part in the rejection of neoplastic lesions before they progress towards a benign or malignant tumour.
Dudek-Peric, Aleksandra M., Garg, Abhishek, Agostinis, Patrizia, Romano, Erminia   +3 more
core   +5 more sources

Immunogenic Cell Death and Immunomodulatory Effects of Cabozantinib

Frontiers in Oncology, 2021
Cabozantinib (XL-184) is a multitarget tyrosine kinase inhibitor (TKI) targeting receptor tyrosine kinases (RTKs) involved in oncogenesis and angiogenesis.
Fabio Scirocchi, Chiara Napoletano, Angelica Pace, Hassan Rahimi Koshkaki, Alessandra Di Filippo, Ilaria Grazia Zizzari, Marianna Nuti, Aurelia Rughetti   +7 more
doaj   +4 more sources

Tumor-intrinsic determinants of immunogenic cell death modalities

OncoImmunology, 2021
The immune system can recognize tumor cells to mount antigen-specific T cell response. Central to the establishment of T cell-mediated adaptive immunity are the inflammatory events that facilitate antigen presentation by stimulating the expression of MHC
Samuel T Workenhe, Jonathan Pol, Guido Kroemer   +2 more
doaj   +2 more sources

Dynamical Boolean Modeling of Immunogenic Cell Death [PDF]

Frontiers in Physiology, 2020
As opposed to the standard tolerogenic apoptosis, immunogenic cell death (ICD) constitutes a type of cellular demise that elicits an adaptive immune response.
Andrea Checcoli, Jonathan G. Pol, Jonathan G. Pol, Aurelien Naldi, Vincent Noel, Vincent Noel, Vincent Noel, Emmanuel Barillot, Emmanuel Barillot, Emmanuel Barillot, Guido Kroemer, Guido Kroemer, Guido Kroemer, Guido Kroemer, Guido Kroemer, Denis Thieffry, Laurence Calzone, Laurence Calzone, Laurence Calzone, Gautier Stoll, Gautier Stoll   +20 more
doaj   +4 more sources

Immunogenicity of cell death driven by immune effectors [PDF]

Journal for ImmunoTherapy of Cancer, 2020
Whether cell death caused by T lymphocytes and natural killer (NK) cells would be immunogenic per se has been a matter of intense debate. Two back-to-back papers from the Melero’s and Pardo’s groups have now resolved this conundrum, demonstrating that T ...
Lorenzo Galluzzi, Guido Kroemer, Giulia Petroni   +2 more
doaj   +3 more sources

Immunogenic Cell Death in Hematological Malignancy Therapy

Advanced Science, 2023
Although the curative effect of hematological malignancies has been improved in recent years, relapse or drug resistance of hematological malignancies will eventually recur.
Zhaoyun Liu, Xintong Xu, Kaining Liu, Jingtian Zhang, Dan Ding, Rong Fu   +5 more
doaj   +3 more sources

Inducers of immunogenic cancer cell death

Cytokine & Growth Factor Reviews, 2013
Recently, cytokine-based pro-tumourigenic signalling has been found to play a major role in the immune system's pro-tumourigenic activity. On the other hand, other recent findings have shown that immunogenic cancer cell death triggered by certain ...
Agostinis, P., Dudek, Aleksandra, Krysko, Dmitri V., Garg, A.D., Ruysscher, D. de, Garg, Abhishek, Agostinis, Patrizia, Krysko, D.V., Dudek, Aleksandra M, Garg, Abhishek D, De Ruysscher, Dirk, Krysko, Dmitri, Dudek, A.M.D.   +12 more
core   +4 more sources

Targeting immunogenic cell death for glioma immunotherapy

Trends in Cancer
Immunogenic cell death (ICD) arouses great interest in targeting glioma, the most common primary brain tumor, to achieve boosted immunotherapy. We discuss the unexpected findings on the induction of Th17 immunity by ICD and propose the best design for ...
Mishchenko, Tatiana A., Gorshkova, Ekaterina N., V. Vedunova, Maria, Turubanova, Victoria D., Krysko, Olga, Krysko, Dmitri   +5 more
core   +3 more sources

Targeting immunogenic cell death in cancer [PDF]

Molecular Oncology, 2020
Immunogenic cell death (ICD) is a type of cancer cell death triggered by certain chemotherapeutic drugs, oncolytic viruses, physicochemical therapies, photodynamic therapy, and radiotherapy. It involves the activation of the immune system against cancer in immunocompetent hosts.
Ahmed, Asma, Tait, Stephen W.G.
openaire   +3 more sources