Results 21 to 30 of about 6,035,777 (295)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Kazutaka Inamura. Justice and Reciprocity in Aristotle’s Political Philosophy

open access: yesRevista de Filosofia Antiga, 2017
Cambridge Classical Studies. Cambridge University Press: Cambridge, 2015, 255p. $ 103,00. ISBN 978-107-11094-6.
André L. C. Sousa
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Evert van Emde Boas, Albert Rijksbaron, Luuk Huitink, Mathieu de Bakker, Cambridge Grammar of Classical Greek

open access: yesActa Universitatis Carolinae Philologica, 2020
Book review: Evert van Emde Boas, Albert Rijksbaron, Luuk Huitink, Mathieu de Bakker, Cambridge Grammar of Classical Greek. Cambridge: Cambridge University Press, 2019, xlii + 811 page.
Dagmar Muchnová
doaj   +1 more source

The fifth gospel: Isaiah in the history of Christianity [PDF]

open access: yes, 2008
Author: Sawyer, John F A Fifth gospel xvii, 281 p.
Uitti, Roger W.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Duas abordagens sobre o escravismo e o comércio de escravos em Angola

open access: yesAfro-Ásia, 2019
Resenha de: CANDIDO, Mariana P. An African Slaving Port and the Atlantic World: Benguela and its Hinterland. Cambridge: Cambridge University Press, 2013. 366p. SILVA, Daniel B. Domingues da.
Gustavo Acioli
doaj   +1 more source

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