Results 31 to 40 of about 6,035,777 (295)

Review of Roger J. Sullivan, An Introduction to Kant\u27s Ethics (1994) [PDF]

open access: yes, 1997
Harry van der Linden\u27s review of: Roger Sullivan, An Introduction to Kant\u27s Ethics.
van der Linden, Harry
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Physician’s changes in management of return visits to the Emergency Department

open access: yesEmergency Care Journal, 2016
Return visits to the Emergency Department (ED) are estimated between 2-3.1%, which impacts ED care costs and wait times. Adverse events for unscheduled return visits (URVs) have been reported to be as high as 30%.
Adrianna Long   +2 more
doaj   +1 more source

Eine Genealogie spanischen Rechtsdenkens [PDF]

open access: yesRechtsgeschichte - Legal History, 2019
Rafael Domingo, Javier Martínez-Torrón (Hg.), Great Christian Jurists in Spanish History (Cambridge Studies in Law and Christianity), Cambridge: Cambridge University Press 2018, xiv + 395 S., ISBN 978-1-108-42807 ...
Daniel S. Allemann
doaj   +1 more source

Bias and the informed observer: A call for a return to Gough [PDF]

open access: yes, 2009
Copyright @ 2009 Cambridge University Press.No abstract ...
Olowofoyeku, AA
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Worship as meaning: a liturgical theology for late modernity [PDF]

open access: yes, 2005
Title: Worship as meaning: a liturgical theology for late modernity. Author: Hughes, Graham Worship as meaning 330 p.
Jacobsen, David Schnasa
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

"Doctoral Research in Cambridge (1922- 1987)" , Archaeological Review from Cambridge, edited by Sarah Taylor, Occasional Paper I, Department of Archaeology, Cambridge University, Spring 1989

open access: yesBulletin of the History of Archaeology, 1992
The Department of Archaeology, Cambridge University (England), has done a great service to scholars interested in the history of archaeology by issuing Occasional Paper 1 under its umbrella publication the Archaeological Review ...
Douglas R. Givens
doaj   +1 more source

CamBridge [PDF]

open access: yesProceedings of the 16th ACM SIGGRAPH International Conference on Virtual-Reality Continuum and its Applications in Industry, 2018
The designer of the virtual environment have been trying for decades to provide the player with more enjoyable, comfortable and also informative user experiences, and yet still fail to ensure that the player follow the preset instructions and even implicit suggestions faithfully and naturally, due to the designer's invisibility during runtime, and the ...
Chanchan Xu, Guangzheng Fei, Honglei Han
openaire   +1 more source

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