Results 71 to 80 of about 6,035,777 (295)

Radical History and the Struggle Revisited: The Cambridge History of South Africa

open access: yesAfrican Studies Quarterly, 2012
Review Essay Carolyn Hamilton, Bernard K. Mbenga and Robert Ross (eds.). 2010. The Cambridge History of South Africa, Volume 1, From Early Times to 1885. Cambridge, UK and New York, New York: Cambridge University Press. xx, 467 pp.
Aran MacKinnon
doaj  

FutureGRID: A Program for long-term research into GRID systems architecture [PDF]

open access: yes, 2008
Proceedings of the 2003 UK e-Science All Hands Meeting, 31st August - 3rd September, Nottingham UKThis is a project to carry out research into long-term GRID architecture, in the University of Cambridge Computer Laboratory and the Cambridge eScience ...
Crowcroft, Jon   +5 more
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Performance modelling of the Cambridge Fast Ring protocol [PDF]

open access: yes, 1988
The Cambridge Fast Ring is high-speed slotted ring. The features that make it suitable for use at very large transmission rates are the synchronous transmission, the simplicity of the medium-access-control protocol, and the possibility of immediate ...
Niemegeers, I.G., Zafirovic-Vukotic, M.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Block Maps between Primitive Uniform and Pisot Substitutions

open access: yes, 2014
In this article, we prove that for all pairs of primitive Pisot or uniform substitutions with the same dominating eigenvalue, there exists a finite set of block maps such that every block map between the corresponding subshifts is an element of this set,
Salo, Ville, Törmä, Ilkka
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Krueger, Roberta L., ed. 2023. The New Cambridge Companion to Medieval Romance. Cambridge: Cambridge University Press. Pp. xviii + 308. ISBN 9781108749589.

open access: yesSELIM
Book review of Krueger, Roberta L., ed. 2023. The New Cambridge Companion to Medieval Romance. Cambridge: Cambridge University Press. Pp. xviii + 308. ISBN 9781108749589.
Charlotte Palmer
doaj   +1 more source

Matching service development to mental health needs: a case study of a rural county [PDF]

open access: yes, 1998
The development of Somerset's mental health services from 1991 to 1996 involved the closure of the county's last long-stay hospital, and its replacement by more local in-patient provision and an expansion of community services. The process and outcome of
Cambridge, P, Carpenter, J, Ring, C
core  

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