Results 31 to 40 of about 7,037 (235)

Camelid immunoglobulins and nanobody technology [PDF]

Veterinary Immunology and Immunopathology, 2009
It is well established that all camelids have unique antibodies circulating in their blood. Unlike antibodies from other species, these special antibodies are devoid of light chains and are composed of a heavy-chain homodimer. These so-called heavy-chain antibodies (HCAbs) are expressed after a V-D-J rearrangement and require dedicated constant gamma ...
Muyldermans, S, Baral, TN, Retarnozzo, VC, De Baetselier, P, De Genst, E, Kinne, J, Leonhardt, H, Magez, Stefan, Nguyen, VK, Revets, H, Rothbauer, U, Stijemans, B, Tillib, S, Wernery, U, Wyns, L, Hassanzadeh-Ghassabeh, G, Saerens, D   +16 more
openaire   +5 more sources

Middle East respiratory syndrome coronavirus infection in camelids [PDF]

, 2022
Middle East respiratory syndrome coronavirus (MERS-CoV) is the cause of a severe respiratory disease with a high case fatality rate in humans. Since its emergence in mid-2012, 2578 laboratory-confirmed cases in 27 countries have been reported by the ...
dPB I&I, Serra Gironella, Joan, Baumgartner, Wolfgang, VPDC pathologie, Bensaid, Albert, Te, Nigeer, Haagmans, Bart L, Haverkamp, Ann Kathrin, Vergara-Alert, Júlia, dPB CR, van den Brand, Judith M A, Ciurkiewicz, Malgorzata, Segalés, Joaquim, van den Brand, Judith M. A., Haagmans, Bart L., Rodon, Jordi, Haverkamp, Ann-Kathrin, van den Brand, Judith M.A.   +17 more
core   +1 more source

Microsatellite-Based Genetic Diversity and Population Structure of Huacaya Alpacas (Vicugna pacos) in Southern Peru

Animals, 2023
The alpaca population mostly consists of the Huacaya phenotype and is widely distributed in Southern Peru. This study aimed to estimate the genetic diversity and population structure of two Huacaya alpaca populations (Ajoyani and Quimsachata) using ...
Deyanira Figueroa, Flor-Anita Corredor, Ruben H. Mamani-Cato, Roberto F. Gallegos-Acero, Nicoll Condori-Rojas, Richard Estrada, Lizeth Heredia, Wilian Salazar, Carlos Quilcate, Carlos I. Arbizu   +9 more
doaj   +1 more source

, Camelidae) and comparisons with other camelids and euungulates

, 2023
Camelids are the only living representatives of the Suborder Tylopoda, and present a unique set of osteo-myological masticatory features, differing from all other extant euungulates. They combine selenodont dentition and rumination with a fused symphysis,
Alvarez, Alicia, Marcos D. Ercoli, Ercoli, Marcos Darío, Moyano, Silvana Rocio, Alicia Álvarez, S. Rocío Moyano   +5 more
core   +1 more source

Past and Recent Effects of Livestock Activity on the Genetic Diversity and Population Structure of Native Guanaco Populations of Arid Patagonia

Animals, 2021
Extensive livestock production and urbanization entail modifications of natural landscapes, including installation of fences, development of agriculture, urbanization of natural areas, and construction of roads and infrastructure that, together, impact ...
Andrés Mesas, Ricardo Baldi, Benito A. González, Virginia Burgi, Alexandra Chávez, Warren E. Johnson, Juan C. Marín   +6 more
doaj   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Advances in Fibre Production Science in South American Camelids and other Fibre Animals

, 2019
Softcover, 17x24Animal fibres from South American camelids and other fibre or wool bearing species provide important products for use by the human population.

core   +1 more source

Does the presence of livestock alter the trophic behaviour of sympatric populations of wild camelids Vicugna vicugna Molina 1782 and Lama guanicoe Müller 1976 (Artiodactyla: Camelidae)? Evidence from Central Andes

Gayana, 2020
We described and compared the diets of two sympatric Andean camelids, during the humid season (austral summer) in a site of Northern Chile, in presence of domestic livestock.
Carlos Tirado, A. Cortés, M. A. Carretero, Francisco Bozinovic   +3 more
doaj  

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

South American Camelids: their values and contributions to people [PDF]

, 2020
South American Camelids (SACs) make several material and non-material contributions to people and are a key component of the Andean biocultural heritage.
Vila, Bibiana Leonor, Arzamendia, Yanina
core   +1 more source