Results 31 to 40 of about 4,888 (191)

A Generative Neuro‐Symbolic AI for Protein Sequence Design

open access: yesAdvanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne   +12 more
wiley   +1 more source

Does the presence of livestock alter the trophic behaviour of sympatric populations of wild camelids Vicugna vicugna Molina 1782 and Lama guanicoe Müller 1976 (Artiodactyla: Camelidae)? Evidence from Central Andes

open access: yesGayana, 2020
We described and compared the diets of two sympatric Andean camelids, during the humid season (austral summer) in a site of Northern Chile, in presence of domestic livestock.
Carlos Tirado   +3 more
doaj  

Effect of progesterone supplementation using 2 different intravaginal devices during a 7-day Ovsynch protocol in lactating dairy cows

open access: yesJournal of Dairy Science
: The objective of this study was to evaluate the effect of progesterone supplementation using 2 different commercially available intravaginal progesterone (P4) devices during a 7 d Ovsynch protocol on pregnancy per artificial insemination (P/AI) in ...
R. Frenkel   +4 more
doaj   +1 more source

Early embryonic death in Equines and Camelids

open access: yesOpen Veterinary Journal, 2022
This paper includes the study about early embryonic death, predisposing factors of early embryonic death and treatment. Early embryonic death refers to the fetal mortality which varies in mare and camelids but most probably not later than 50 days of gestation.
Rehan Ashraf   +3 more
openaire   +4 more sources

Enhanced antiviral immunity and dampened inflammation in llama lymph nodes upon MERS-CoV sensing: bridging innate and adaptive cellular immune responses in camelid reservoirs

open access: yesFrontiers in Immunology, 2023
Middle East respiratory syndrome coronavirus (MERS-CoV) infection can cause fatal pulmonary inflammatory disease in humans. Contrarily, camelids and bats are the main reservoir hosts, tolerant for MERS-CoV replication without suffering clinical disease ...
Jordi Rodon   +9 more
doaj   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

open access: yesAngewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber   +4 more
wiley   +1 more source

Humans are not unique: difficult birth is common in placental mammals

open access: yesBiological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

Large-Scale Embryo Transfer Operation in Dromedary Camels: Retrospective Analysis of the Association Between Key Clinical Factors and the 2-Month Pregnancy Rate

open access: yesAnimals
ET is used in camel reproduction to increase the reproductive potential of elite females selected for production and show. This retrospective study analyzed the association between factors related to embryo flushing (flushing fluid turbidity and debris),
Taher Kamal Osman   +2 more
doaj   +1 more source

From Caffeine to Aspirin: Everyday Molecules as Triggers for Genetically Encoded Proximity Systems

open access: yesChemistry – A European Journal, EarlyView.
This Perspective article highlights how familiar dietary ingredients and over‐the‐counter (OTC) drugs (such as caffeine and its metabolites, SA, and aspirin) can be repurposed as clinically translatable chemical triggers for genetically encoded proximity systems.
Mingguang Cui   +5 more
wiley   +1 more source

Nanobodies: a promising approach to treatment of viral diseases

open access: yesFrontiers in Immunology
Since their discovery in the 1990s, heavy chain antibodies have garnered significant interest in the scientific community. These antibodies, found in camelids such as llamas and alpacas, exhibit distinct characteristics from conventional antibodies due ...
Vitória Meneghetti Minatel   +5 more
doaj   +1 more source

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