Results 71 to 80 of about 4,888 (191)
Camelids are commonly found in coastal Peruvian archaeological sites dated to the Prehispanic period but are nowadays missing on the coast. Because of their modern geographical distribution it has been suggested that these animals were brought to the ...
Nicolas Goepfert +3 more
doaj +1 more source
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
NeoUngulatesDiet: A database of ungulate diets in the Neotropics
Abstract Ungulates play a crucial ecological role in tropical forests by influencing various ecosystem processes, including herbivory, seed dispersal and predation, and seedling recruitment. These large mammalian herbivores, including tapirs, camelids, cervids, and peccaries, have a significant impact on plant community structure, composition, and ...
Laís Lautenschlager +9 more
wiley +1 more source
Antibody–Drug Conjugates and Peptide–Drug Conjugates: Current Understandings and Future Perspectives
The graphic summarizes the design principles, intracellular trafficking, clinical progress, challenges, and future directions of antibody–drug conjugates (ADCs) and peptide–drug conjugates (PDCs). ADCs consist of a tumor‐targeting antibody, a chemical linker, and a potent payload, whereas PDCs use peptide ligands to deliver cytotoxic, radionuclide, or ...
Ruxi Zheng +9 more
wiley +1 more source
Explotación de recursos animales y producción textil durante el holoceno en Antofagasta de la sierra
El estudio morfológico de fibras recuperadas del sitio Quebrada Seca 3,localizado en un ecosistema de altura, consideró 204 muestras, tomandoen cuenta las variables médula, grosor y color.
María del Carmen Reigadas
doaj +1 more source
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley +1 more source
Since they were first described in 1993, it was found that recombinant variable fragments (rVHHs) of heavy-chain antibodies (HCAbs) from Camelidae have unusual biophysical properties, as well as a special ability to interact with epitopes that are ...
A. Ferrari +5 more
doaj +1 more source
Sequencing KRT71 as a candidate gene for hair shape variation in dromedary camels
Mammalian breeds within different species display a distinct variation in hair shape. Genetic variants within the Keratin 71 (KRT71) gene were linked to curly hair in multiple species, making it a suitable candidate for investigating hair shape in under ...
doaj +1 more source
En este trabajo presentamos un análisis detallado de las arqueofaunas recuperadas en el sitio Corral Alto (Quebrada de Miriguaca) a fin de abordar los patrones de explotación de recursos faunísticos implementados por las comunidades agropastoriles que ...
Jennifer Grant, Patricia Escola
doaj +1 more source
Explotación de recursos animales y producción textil durante el holoceno en Antofagasta de la sierra
El estudio morfológico de fibras recuperadas del sitio Quebrada Seca 3,localizado en un ecosistema de altura, consideró 204 muestras, tomandoen cuenta las variables médula, grosor y color.
María del Carmen Reigadas
doaj

