Results 171 to 180 of about 51,149 (268)
Abstract Objective Long‐term memory deficits are often seen in patients with temporal lobe epilepsy (TLE). Recently, studies showed that patients with hippocampal sclerosis (HS) type 2, which presents with severe neuron loss in CA1 only, performed within the normal range. However, up to 30% of HS type 2 cases have memory deficits.
Henrique Cruz +10 more
wiley +1 more source
Organic neuromorphic electronics powering intelligent sensory and edge computing systems
Organic electronic materials are promising candidates for neuromorphic sensing applications, including chemical, physical, visual, and multimodal sensing, owing to their mechanical softness, biocompatibility, and intrinsic ionic–electronic coupling.
Seungjun Woo +5 more
wiley +1 more source
CaMKII as a Multimodal Signalling Hub in Neural Connectivity and Vulnerability. [PDF]
Olliff S, Sundaramoorthy V.
europepmc +1 more source
Monitoring CaMKII in Mitochondria
Kevin R. Murphy +8 more
openaire +1 more source
Efferocytosis: Signaling Pathways and New Therapeutic Strategies for Diseases
1. Efferocytosis coordinates molecular signaling and metabolic reprogramming to resolve inflammation. 2. Efferocytosis dysfunction underlies four conserved pathological hallmarks across diseases. 3. Therapeutic strategies targeting efferocytosis should be context‐dependent: enhance or inhibit based on disease type. ABSTRACT Efferocytosis—the phagocytic
Lei Wang +6 more
wiley +1 more source
Ca<sup>2+</sup>/calmodulin-dependent protein kinase II and protein kinase G independently contribute to acutely enhance myocardial compliance with stretch. [PDF]
Leite-Moreira AM +4 more
europepmc +1 more source
Mechanisms of CaMKII Activation
Calcium/calmodulin (Ca2+/CaM) dependent protein kinase II (CaMKII) has emerged as a key nodal protein in the regulation of cardiac physiology and pathology. Due to the particularly elegant relationship between the structure and function of the kinase, CaMKII is able to translate a diverse set of signaling events into downstream physiological effects ...
openaire +1 more source
The steroid hormone ADIOL emerges as a key mediator of fasting–and caloric restriction–induced healthspan benefits in C. elegans. These regimens activate ADIOL production, which acts through the estrogen receptor β homolog NHR‐91 to reduce neural kynurenic acid levels and enhance healthspan independently of lifespan. ADIOL supplementation, even late in
Ana Guijarro‐Hernández +6 more
wiley +1 more source
CaMKII nucleates an osmotic protein supercomplex to induce cellular bleb expansion. [PDF]
Fujii Y +3 more
europepmc +1 more source
P2X7 is an important mediator of BMP9-induced osteogenic differentiation of mesenchymal stem cells. [PDF]
Zhang L +6 more
europepmc +1 more source

