Results 91 to 100 of about 1,724,681 (307)

Promoting Treg Polarization‐Mediated Anti‐Scar and Appendage Regeneration in Wound Healing

open access: yesAdvanced Science, EarlyView.
This study develops a PLGA@LA‐BMP4‐PG bilayer scaffold to address scar formation and appendage loss in skin repair. The piezoelectric PLA layer enhances cell migration via electric fields, while GelMA delivers LA promoting Tregs polarization and BMP4 inhibiting FBs differentiation.
Yiwen Yang   +10 more
wiley   +1 more source

Efficacy of Online Training for Improving Camp Staff Competency

open access: yes, 2018
Preparing competent staff is a critical issue within the camp community. This quasi-experimental study examined the effectiveness of an online course for improving staff competency in camp healthcare practices among college-aged camp staff and a ...
Alice M. Brawley   +22 more
core   +1 more source

Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai   +15 more
wiley   +1 more source

Irrelevant natural extension for choice functions [PDF]

open access: yes, 2019
We consider coherent choice functions under the recent axiomatisation proposed by De Bock and De Cooman that guarantees a representation in terms of binary preferences, and we discuss how to define conditioning in this framework.
Miranda, Enrique, Van Camp, Arthur
core  

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

open access: yesAdvanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia   +6 more
wiley   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

open access: yesAdvanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian   +5 more
wiley   +1 more source

La cadira Joëlette: una mesura i suport addicional que promou la inclusió de l’alumnat amb discapacitat motriu als camps d’aprenentatge

open access: yesRevista Catalana de Pedagogia
El Camp d’Aprenentatge de les Valls d’Àneu (Servei Educatiu del Departament d’Educació i Formació Professional) ha dut a terme dues estades adaptades, seguint els preceptes de l’escola inclusiva.
Marta Naharro i Via   +3 more
doaj  

La lettre de Nusreta Sivac

open access: yesAstérion, 2011
Nusreta Sivac, ancienne juge à Prijedor, détenue au camp d’Omarska en 1992, retrace quant à elle le processus qui conduit de l’occupation de la ville par l’armée nationaliste serbe au licenciement des non Serbes, à l’expulsion des logements, à l ...
Nusreta Sivac
doaj   +1 more source

Synergistic effect of phosphodiesterase 4 inhibitor and serum on migration of endotoxin-stimulated macrophages. [PDF]

open access: yes, 2018
Macrophage migration is an essential step in host defense against infection and wound healing. Elevation of cAMP by inhibiting phosphodiesterase 4 (PDE4), enzymes that specifically degrade cAMP, is known to suppress various inflammatory responses in ...
Catherine Jin, S-L   +7 more
core  

Anti‐Apoptotic and Neurite‐Protective Nanomedicine Augments Embryonic Stem Cells‐Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery

open access: yesAdvanced Science, EarlyView.
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen   +14 more
wiley   +1 more source

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