Results 91 to 100 of about 1,737,217 (304)

Efficacy of Online Training for Improving Camp Staff Competency

open access: yes, 2018
Preparing competent staff is a critical issue within the camp community. This quasi-experimental study examined the effectiveness of an online course for improving staff competency in camp healthcare practices among college-aged camp staff and a ...
Alice M. Brawley   +22 more
core   +1 more source

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan   +12 more
wiley   +1 more source

“The Vast Experiment”: The New Brunswick Militia’s 1865 Camp of Instruction [PDF]

open access: yes, 2012
In July 1865, almost 1,000 New Brunswick militiamen assembled in Fredericton for a twenty-four day Camp of Instruction. This was the first time peacetime militia training on this scale was ever attempted in British North America.
Wilson, J. Brent
core   +1 more source

IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome

open access: yesAdvanced Science, EarlyView.
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao   +13 more
wiley   +1 more source

Przez język ukrycia po słowo na „g”. Kim są bohaterowie czasów queer before gay?

open access: yesPoznańskie Studia Slawistyczne, 2019
Who (and what) was silent about the story told by heteronormative society? And how is the fragment of this story seen by “Others”? The article shows that the time of “queer before gay” includes (in Polish) not only well-known names such as: aunt or pedal,
Tomasz Łukasz Nowak
doaj   +1 more source

Regulation of reactivated elongation in lysed cell models of teleost retinal cones by cAMP and calcium. [PDF]

open access: yes, 1986
Teleost retinal cones elongate in the dark and contract in the light. In isolated retinas of the green sunfish Lepomis cyanellus, cone myoids undergo microtubule-dependent elongation from 5 to 45 micron. We have previously shown that cone contraction can
Ackland, N, BURNSIDE, Beth, Gilson, C
core   +1 more source

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

open access: yesAdvanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian   +13 more
wiley   +1 more source

Irrelevant natural extension for choice functions [PDF]

open access: yes, 2019
We consider coherent choice functions under the recent axiomatisation proposed by De Bock and De Cooman that guarantees a representation in terms of binary preferences, and we discuss how to define conditioning in this framework.
Miranda, Enrique, Van Camp, Arthur
core  

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

open access: yesAdvanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu   +11 more
wiley   +1 more source

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