Results 161 to 170 of about 646,261 (261)

A Precision‐Delivered Singlet Oxygen Generator With an Inbuilt Safety Switch for Induction of Pancreatic Beta Cell Stress and Death

Angewandte Chemie, EarlyView.
ROXendin668 is a peptidic GLP‐1 receptor agonist that generates toxic singlet oxygen upon irradiation with far‐red light. Pancreatic beta cells can be photo‐ablated in a spatiotemporally controlled manner. This approach has the potential to provide a safer alternative to streptozotocin or alloxan for creating model systems for type 1 diabetes research.
Kilian Roßmann, Owen Bendor‐Samuel, Christopher Carlein, Kaja Rupar, Leticia Prates Roma, Ramona Birke, Tolga Soykan, Ingo Breng, Andreas Oder, Iona Davies, Ben Jones, Alice Adriaenssens, Michelle M. Martinez Irizarry, Rachael Morara, Martin Lehmann, Amelia K. Linnemann, David J. Hodson, Johannes Broichhagen   +17 more
wiley   +2 more sources

A Personal Interview With Dr. Jon C. Dalton

Journal of College Orientation, Transition, and Retention, 2010
Jeanine Ward-Roof
doaj   +1 more source

Cardiac camp: An outreach program to build health literacy among underrepresented in medicine adolescents and increase diversity in medicine. [PDF]

J Educ Health Promot
Mataraarachchi N, Ainooson J, Hernandez DE, Pepic L, Raby E, Tanchoco E, Phan BAP.   +6 more
europepmc   +1 more source

Grilling chicken at Freshman Camp

, 1950
A photograph of freshman students grilling chicken as part of Freshman Camp, held on East Campus at Springfield College, ca. 1950’s. Three women appear in the photograph, cooking pieces of chicken on a grill on the evening.

core  

Olfactory Function in Cystic Fibrosis: Outcome Measures, Olfactory Dysfunction Prevalence and the Impact of Management—A Systematic Review and Meta‐Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction (OD) is an increasingly recognized but under‐investigated comorbidity of cystic fibrosis (CF). Its prevalence, assessment methods, and response to CF‐directed treatment, including highly effective modulator therapy (HEMT) remains incompletely characterized.
Luca Cox, Kofi Cox, Katherine Whitcroft, Susanne Weise, Sonal Kansra, Eishaan Bhargava   +5 more
wiley   +1 more source

Terahertz Photons Ameliorate Traumatic Brain Injury and Reduce Neuroinflammation via the Cyclic Adenosine Monophosphate Signaling Pathway. [PDF]

Research (Wash D C)
Liu J, Zhao X, Zhong Y, Yin J, Wu H, Zhang T, Yu Y, Jiang R, Wang Y, Chang C.   +9 more
europepmc   +1 more source

Astrocyte SMN Restoration and Forskolin Treatment Improve SMA Synaptic Pathology

Annals of Neurology, EarlyView.
Objective Early phenotypic presentation of central afferent synapse dysfunction within patients with spinal muscular atrophy (SMA) represents a key target for therapeutic development; however, the underlying disease mechanisms remain unresolved. By further investigating motor neuron synapse and peri‐synaptic astrocyte process (PAP) defects in human SMA
Emily Welby, Xiaojie Liu, Melinda Wojtkiewicz, Linda Berg Luecke, Rebekah L. Gundry, Qing‐Song Liu, Allison D. Ebert   +6 more
wiley   +1 more source

6PPD-Quinone Induces Anxiety-like Behavior in Mice: A Potential Mechanism Shared Across PPD-Quinones. [PDF]

Toxics
Xu S, Gao L, Yu Y, Kang Y, Chen X, Wang SL, Ruan Z.   +6 more
europepmc   +1 more source

Alkoxyethyl Acetate Electrolytes for High‐Voltage Lithium Metal Batteries

Angewandte Chemie, EarlyView.
We designed a fluorinated alkoxyethyl acetate solvent for high‐voltage Li‖NMC811 batteries. Introducing a carbonyl group disrupts symmetric bidentate solvation, while terminal fluorination enhances high‐voltage stability and reversible Li plating/stripping. The tailored solvation promotes a robust cathode electrolyte interphase, substantially extending
Xinlin Li, Xianyang Wu, Xueping Qin, Sapna L. Ramesh, Hasnain Hafiz, Jeffrey Lopez, Changzhi Ai, Matthew Li, Rachid Amine, Meinan He, Chi‐Cheung Su, Khalil Amine   +11 more
wiley   +1 more source

Targeting P2Y₁₄R inhibits proliferation of cervical cancer cells and organoids and activates cAMP/PKA/CREB signaling pathway. [PDF]

Purinergic Signal
Li R, Xiong HY, Chen SY, Tang Y, Ma WB.
europepmc   +1 more source