Results 191 to 200 of about 2,046,966 (405)

Some Immunological and Hematological Parameters among Refugees in Kawergosk Camp – Erbil Governorate

, 2019
Tanya S. Salih, Safa Safin Haydar, Muhsin H. Ubeid, Ameena S. M. Juma   +3 more
openalex   +2 more sources

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

Advanced Science, EarlyView.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu, Yawei Shen, Robert J. Barndt, Karim Sallam, Ying Tang, Cameron E. Brown, Xiao Li, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu   +10 more
wiley   +1 more source

The master virulence regulator PhoP dictates carbon metabolism by controlling cyclic AMP synthesis in Salmonella. [PDF]

PLoS Biol
Pokorzynski ND, Sams-Dodd EC, Esneault C, Jones KA, Campagna SR, Groisman EA.   +5 more
europepmc   +1 more source

Cilia have high cAMP levels that are inhibited by Sonic Hedgehog-regulated calcium dynamics

Proceedings of the National Academy of Sciences of the United States of America, 2016
B. Moore, Ann N. Stepanchick, Paul H. Tewson, Cassandra M. Hartle, Jin Zhang, A. Quinn, T. Hughes, T. Mirshahi   +7 more
semanticscholar   +1 more source

Book Review: All About the Beat [PDF]

, 2013
Camp, Brooke
core   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Supporting self-reliance for displaced and host populations: insights from the Self-Reliance Index across 16 countries. [PDF]

BMJ Glob Health
Stark L, Jorgenson Diener K, Leeson K, Singh S, Meerdink N, Seff I.   +5 more
europepmc   +1 more source

Quantifying the Single‐Cell Morphological Landscape of Cellular Transdifferentiation through Force Field Reconstruction

Advanced Science, EarlyView.
This study reconstructs the driving force field of fibroblast‐to‐neuron transdifferentiation from sparse single‐cell images by decomposing it into flux and time‐dependent potential gradient, extending the landscape‐flux framework to non‐steady‐state systems.
Chudan Yu, Chuanbo Liu, Erkang Wang, Jin Wang   +3 more
wiley   +1 more source

Associations between refugee camp living and duration lived in refugee camps with health outcomes: A cross-sectional analysis of the Annual Survey of Refugees, 2021-2022. [PDF]

PLoS One
Thapa K, Sabbah L, AlHeresh R, Saadi A.
europepmc   +1 more source

cAMP-induced phosphorylation of 26S proteasomes on Rpn6/PSMD11 enhances their activity and the degradation of misfolded proteins

Proceedings of the National Academy of Sciences of the United States of America, 2015
S. Lokireddy, N. Kukushkin, A. Goldberg
semanticscholar   +1 more source