Results 21 to 30 of about 283,299 (265)
Characterization of Constitutively Activating Eel Follicle-Stimulating Hormone Receptor
Journal of Animal Reproduction and Biotechnology, 2019 This study aimed to investigate the function of the constitutively activating mutation D540G on eel FSHR activity by in vitro functional studies. Site-directed mutagenesis was carried out to generate the D-to-G mutation at position 540 of the pcDNA3-eel ...
Jeong-Soo Kim +2 more
doaj +1 more source
“Beef Jerky in a Ball Gown”: The Camp Excesses of Titus Andromedon in Unbreakable Kimmy Schmidt
Open Cultural Studies, 2017 In this essay, we look at Titus Andromedon from the Netflix-sitcom Unbreakable Kimmy Schmidt (2014-) as a singular phenomenon in contemporary TV: a black queen whose use of camp distances him from stereotypes, but connects him with audiences.
Dexl Carmen, Horn Katrin
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Un automne à PinceventLe campement magdalénien du niveau IV20
Les Nouvelles de l’Archéologie, 2015 Since 1964, when the Magdalenian site of Pincevent was discovered by A. Leroi-Gourhan and his team, the methods of excavation and analysis have evolved.
Michèle Julien, Claudine Karlin
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
BMC Sports Science, Medicine and RehabilitationThe aim of this cross-sectional study was to establish age and sex-specific normative values for strength, power, agility and flexibility assessed by field-based tests in young volleyball players aged 10–18 years who were actively training and competing ...
Vladimir Grbić +4 more
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Neoclassicism and Camp in Sir William Hamilton’s Naples
ABO : Interactive Journal for Women in the Arts 1640-1830, 2019 Susan Sontag, in her now-classic “Notes on Camp” (1964), traces the origins of camp to the eighteenth century (13, 14, 33). And although it is precisely the baroque and rococo art movements against which Winckelmann rebelled that Sontag identifies as ...
Ersy Contogouris
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Journal of Inflammation Research, 2021 Xinwei Cao,1 Yajun Li,1 Jianrong Shi,2 Huifang Tang1 1Department of Pharmacology, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, People’s Republic of China; 2Department of Clinical Laboratory, Children’s Hospital ...
Cao X, Li Y, Shi J, Tang H
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source