Results 31 to 40 of about 646,261 (261)

The Potentially Therapeutic Role of EPAC in Curbing the Process of Idiopathic Pulmonary Fibrosis via Differential Cellular Pathways

open access: yesJournal of Inflammation Research, 2021
Xinwei Cao,1 Yajun Li,1 Jianrong Shi,2 Huifang Tang1 1Department of Pharmacology, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, People’s Republic of China; 2Department of Clinical Laboratory, Children’s Hospital ...
Cao X, Li Y, Shi J, Tang H
doaj  

Famous First Words @ Writers' Camp

open access: yes, 2020
The inspiration for Writers' Camp @ ZSR came after a group of ZSR librarians heard Jane McGonigal present “Find the Future: The Game” during the American Library Association’s 2014 Annual Conference.
ZSR Writers' Camp 2020
core  

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Functional Recovery and Return to Duty Following Minimally Invasive Surgery for Hallux Valgus: A Retrospective Review in Active-Duty Military Personnel

open access: yesFoot & Ankle Orthopaedics
Background: Hallux valgus can severely limit physical function in demanding professions like military service. Traditional open surgeries have shown limited success in achieving rapid recovery and full functional return.
Colin Mizuo DPM, FACFAS   +3 more
doaj   +1 more source

El projecte KBIP a l’Institut Baix Camp de Reus. Una metodologia d’innovació per a la millora dels resultats educatius amb alumnat amb NEE

open access: yesRevista Catalana de Pedagogia, 2020
Des de l’any 2009, a l’INS Baix Camp de Reus treballem amb alumnes amb necessitats específiques de suport educatiu (NESE) en el projecte basat en el treball coŀlaboratiu, iniciat al Quebec, KBIP (Knowledge Building International Project), el qual, a ...
Teresa Morales, Carme Aragonès
doaj  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Oncology Camp Participation and Psychosocial Health in Children Who Have Lived with Cancer—A Pilot Study

open access: yesCurrent Oncology
Children with lived cancer experience encounter adversity, therefore experiences promoting psychosocial health are necessary. This pilot study determined the impact of recreational oncology camps (ROC) on resilience, hope, social support, and mental well-
Sarah O’Connell   +3 more
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Antiplatelet activity of deferiprone through cyclooxygenase-1 inhibition

open access: yesPlatelets, 2020
Thalassemia patients are susceptible to both iron overload and thromboembolism. Deferiprone is an iron chelator that shows an antiplatelet activity and thus may alleviate platelet hyperactivation in thalassemia.
Ngan Thi Tran   +4 more
doaj   +1 more source

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