Results 211 to 220 of about 488,915 (298)

Mechanophotochemistry: Lighting up EDA Complexes in the Solid State

open access: yesAngewandte Chemie, EarlyView.
Examples of mechanophotochemical EDA complex‐mediated radical reactions, including a Giese reaction, a C─S cross‐coupling reaction, a phosphorylation reaction, and a sulfonylation reaction are shown to rapidly proceed in air using visible light excitation.
Aniket Kumar Srivastawa   +1 more
wiley   +2 more sources

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

open access: yesAngewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani   +7 more
wiley   +1 more source

Psychosis Mental Health Campaigns: A Scoping Review of Strategies and Outcomes. [PDF]

open access: yesEarly Interv Psychiatry
Straub KT   +4 more
europepmc   +1 more source

Scrolling toward prevention: reimagining trauma education through social media. [PDF]

open access: yesTrauma Surg Acute Care Open
Hoekman AH   +3 more
europepmc   +1 more source

Upcycling agricultural residues into polyhydroxyalkanoates through pilot-scale mixed microbial culture processes. [PDF]

open access: yesFront Bioeng Biotechnol
Pesante G   +9 more
europepmc   +1 more source

Thinking Outside the Binding Site: A Self‐Encapsulating Kinase Inhibitor Remodels Its Pocket to Achieve Selectivity

open access: yesAngewandte Chemie International Edition, EarlyView.
To make exceptionally effective drugs, thinking “outside the binding site” is required. This work reveals that counterintuitive targeting of a kinase‐conserved region can lead to highly selective binding. Inhibitor discovery coupled to x‐ray crystallography shows that a network of noncanonical interactions and long‐range effects of distant unique amino
Nico J. Seidler   +20 more
wiley   +1 more source

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