Results 101 to 110 of about 201,283 (312)
Advanced Science, EarlyView.Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu +11 more
wiley +1 more source
Camping Tourism in the Role of Creating Competitiveness of the Croatian Tourism
Acta Economica et Turistica, 2020 Of all definitions, tourism can be defined as a phenomenon based on movement and travel. Tourism is the most adaptable of all branches of tourism, and it is exposed to numerous influences, such as political, social, and personal.
Andreja Rudančić, Katarina Kulić
doaj
Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor
Advanced Science, EarlyView.Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang +4 more
wiley +1 more source
The use of values to understand visitors to natural areas: a study of campers on the Murray River [PDF]
, 2005 In Australia, protected areas such as national parks have extensive strategies in place to ensure the natural environment is conserved, and visitors are provided with a range of opportunities for satisfying experiences.
Winter, Caroline
core
Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment
Advanced Science, EarlyView.Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun +5 more
wiley +1 more source
Actual causation and the art of modeling [PDF]
, 2010 We look more carefully at the modeling of causality using structural equations. It is clear that the structural equations can have a major impact on the conclusions we draw about causality. In particular, the choice of variables and their values can also
Halpern, Joseph Y. +1 more
core +2 more sources
Advanced Science, EarlyView.This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon +21 more
wiley +1 more source
How to Develop the Korean Camping Culture and Industry: Focused on Camping Site Selection Attributes
SAGE OpenThis study aims to promote camping as a healthy leisure culture rather than a passing trend. A literature review, expert interviews, and consultations were conducted to identify key factors influencing campers’ choice of campgrounds.
Hyungchul Joo, Yoonso Choi
doaj +1 more source
Studies on the Reduction of Radon Plate-Out
, 2015 The decay of common radioactive gases, such as radon, produces stable isotopes by a sequence of daughter particles with varied half-lives. These daughter particles are a significant source of gamma, neutron, and alpha particle backgrounds that can mimic ...
Bruemmer, M. +4 more
core +1 more source
Advanced Science, EarlyView.Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong +21 more
wiley +1 more source