Results 81 to 90 of about 201,283 (312)

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

open access: yesAdvanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska   +14 more
wiley   +1 more source

Enhancing Outdoor Equipment Marketing through Augmented Reality: A Case Study of Sekaben Camp

open access: yesJurnal Sisfokom
Augmented Reality (AR) has the potential to transform product marketing by creating immersive and interactive experiences. This study presents the development of an AR-based application to enhance the marketing of outdoor equipment at Sekaben Camp, a ...
Tri Sugihartono   +2 more
doaj   +1 more source

Competitive cAMP antagonists for cAMP-receptor proteins.

open access: yesJournal of Biological Chemistry, 1984
The two exocyclic oxygen atoms at phosphorus of cAMP have been replaced by a sulfur atom or by a dimethylamino group. These substitutions introduce chirality at the phosphorus atom; therefore, two diastereoisomers are known for each derivative: (SP)-cAMPS, (RP)-cAMPS, (SP)-cAMPN(CH3)2, and RP-cAMPN(CH3)2.
Haastert, Peter J.M. van   +5 more
openaire   +3 more sources

New Zealand outdoor recreation benefits [PDF]

open access: yes, 2007
Millions of people participate in outdoor recreation activities in New Zealand every year. Economic recreation studies in the country concentrate mostly on market values. Market values only present part of the outdoor recreation benefit; while non-market
Kaval, Pamela, Yao, Richard
core   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

open access: yesAdvanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao   +12 more
wiley   +1 more source

Risk and Recreation: Differences Due to Gender, Age and Education [PDF]

open access: yes, 1999
Dr. Burger explores the differences in risk perception due to gender, age and education with regard to recreation activities on former U.S.
Burger, Joanna
core   +2 more sources

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan   +12 more
wiley   +1 more source

Ephemeral Domesticity: Campsite Authors

open access: yesInteriority
The fleeting nature of life and the resulting transformation of inhabited spaces into artefacts that take on different socio-spatial forms through temporary shelters such as cabins, tents, and trailers is a major theme explored particularly in the 1960s ...
Julia Capomaggi
doaj   +1 more source

Itinéraire d’une plage méditerranéenne : Argelès-sur-Mer

open access: yesGéographie et Cultures, 2008
La station d’Argelès-sur-Mer, réputée surtout pour ses multiples campings, bénéficie également d’une longue plage sablonneuse. Son évolution témoigne d’une attractivité durable et renouvelée par des usages multiples.
Anthony Simon
doaj   +1 more source

Guyasuta: Warrior, Estate, and Home to Boy Scouts [PDF]

open access: yes, 2011
For nearly a century, Camp Guyasuta has been “an ideal place for Boy Scouts to live out their Handbook, to dream and be inspired and become good Americans.” Situated on roughly 130 acres in a deep valley between Aspinwall and Sharpsburg, Guyasuta is the ...
Galloway, Edward A
core   +1 more source

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