Results 61 to 70 of about 201,283 (312)

Mission-Market Tensions and Nonprofit Pricing [PDF]

open access: yes, 2008
Private not-for-profit organizations combine characteristics of a public sector agency with those of a private, proprietary firm. In particular, nonprofits are required to address designated social missions while breaking even financially. This structure
Dennis R. Young, Taehyun Jung
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Restaurant-based intervention to facilitate healthy eating choices and the identification of allergenic foods at a family-oriented resort and a campground

open access: yesBMC Public Health, 2017
Background Restaurant-based interventions can be an enjoyable way to encourage healthier eating choices by all members of a family. Thus, the principal aims of this study were a) to promote healthy diets by increasing healthy food offerings and b) to ...
Lucia Tarro   +7 more
doaj   +1 more source

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

open access: yesAdvanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia   +5 more
wiley   +1 more source

Coverage of the Measles-Rubella mass camping vaccination in southern Tehran, Iran

open access: yesPayesh, 2005
Objectives: The ministry of health and medical education in Iran launched a nation-wide campaign against measles and rubella (MR) in December 2003. The target population in southern Tehran covered by Tehran university of medical included 590000 people ...
Majd Zadeh SR   +6 more
doaj  

E.P. Meinecke and the Development of the Modern Auto Campground

open access: yesIdeAs, 2019
Recreational camping began in the United States in the 1860s after the conclusion of the American Civil War. It was an antimodern response to the rapid industrialization and urbanization that had begun to sweep through America. Americans embraced many of
Terence Young
doaj   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

Conference Reimagined. Postcards, Letters, and Camping Together in Undressed Places

open access: yesDigithum, 2019
In this paper, five authors account for the rethinking of a conference as a series of postcards, letters, rules and silent moments so that traditional hierarchies of knowledge could be overturned or, at least, sidelined.
Soile Veijola   +4 more
doaj  

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