Results 191 to 200 of about 42,673 (234)
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Chemische Berichte, 1976
AbstractDie Anwendungsbreite und die Selektivität der autoxidativen Überführung von Desoxycamptothecin‐ in Camptothecinderivate wird untersucht.
Karsten Krohn +2 more
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AbstractDie Anwendungsbreite und die Selektivität der autoxidativen Überführung von Desoxycamptothecin‐ in Camptothecinderivate wird untersucht.
Karsten Krohn +2 more
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Liposomal delivery of camptothecins
Pharmaceutical Science & Technology Today, 2000The use of liposomal drug delivery systems to improve the therapeutic index of pharmaceutical agents is exemplified by camptothecin-based drugs. This highly active class of anticancer agents possesses a unique mechanism of action with some inherent shortcomings, which might have been solved by liposomal formulation.
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Camptothecin Radiation Sensitization
2003The camptothecin analog CPT-11 has recently been approved for the treatment of 5-fluorouracil (5-FU)-resistant colorectal cancer (1), thus opening a new chapter in chemotherapeutic radiation sensitization. The camptothecins (CPT) are potent radiation sensitizers and are in their infancy in clinical studies.
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DFT studies of camptothecins cytotoxicity II. Protonated lactone forms of camptothecin
Computational and Theoretical Chemistry, 2021Marek Štekláč, Martin Breza
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