Results 31 to 40 of about 1,245,546 (143)
Osteopetrosis and Its Relevance for the Discovery of New Functions Associated with the Skeleton
International Journal of Endocrinology, Volume 2015, Issue 1, 2015., 2015 Osteopetrosis is a rare genetic disorder characterized by an increase of bone mass due to defective osteoclast function. Patients typically displayed spontaneous fractures, anemia, and in the most severe forms hepatosplenomegaly and compression of cranial facial nerves leading to deafness and blindness.
Amélie E. Coudert +4 more
wiley +1 more source
Renal Biopsy: Use of Biomarkers as a Tool for the Diagnosis of Focal Segmental Glomerulosclerosis
Disease Markers, Volume 2014, Issue 1, 2014., 2014 Focal segmental glomerulosclerosis (FSGS) is a glomerulopathy associated with nephrotic syndrome and podocyte injury. FSGS occurs both in children and adults and it is considered the main idiopathic nephrotic syndrome nowadays. It is extremely difficult to establish a morphological diagnosis, since some biopsies lack a considerable quantifiable number ...
Crislaine Aparecida da Silva +9 more
wiley +1 more source
Camurati-Engelmann disease: failure of response to bisphosphonates: report of two cases
, 2015 Camurati-Engelmann disease is a rare bone disorder characterized by cortical thickening of the diaphysis of tubular bones, with sparing of the epiphysis.
Coimbra, I +5 more
core +1 more source
MedComm – Oncology, Volume 4, Issue 3, September 2025.TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi +5 more
wiley +1 more source
BioMed Research International, Volume 2014, Issue 1, 2014., 2014 Most researchers agree that idiopathic scoliosis (IS) is a multifactorial disease influenced by complex genetic and environmental factors. The onset of the spinal deformity that determines the natural course of the disease, usually occurs in the juvenile or adolescent period.
Roman Nowak +4 more
wiley +1 more source
Scientifica, Volume 2013, Issue 1, 2013., 2013 Although it has long been recognized that inflammation, a consequence of immune‐driven processes, significantly impacts bone turnover, the degree of centralization of skeletal and immune functions has begun to be dissected only recently. It is now recognized that formation of osteoclasts, the bone resorbing cells of the body, is centered on the key ...
M. Neale Weitzmann +2 more
wiley +1 more source
Skeletal Dysplasias Associated with Mild Myopathy—A Clinical and Molecular Review
BioMed Research International, Volume 2010, Issue 1, 2010., 2010 Musculoskeletal system is a complex assembly of tissues which acts as scaffold for the body and enables locomotion. It is often overlooked that different components of this system may biomechanically interact and affect each other. Skeletal dysplasias are diseases predominantly affecting the development of the osseous skeleton.
Katarzyna A. Piróg +2 more
wiley +1 more source
, 2019 : Camurati-Engelmann disease or progressive diaphyseal dysplasia is a rare autosomal dominant sclerosing bone dysplasia. Mainly the skull and the diaphyses of the long tubular bones are affected.
Boudin, Eveline +4 more
core +1 more source
, 2009 A displasia diafisária progressiva ou doença de Camurati-Engelmann é uma doença rara, caracterizada por dor e fraqueza muscular dos membros afetados e espessamento progressivo da cortical diafisária dos ossos longos.
Frederico Pinto +2 more
core +1 more source
, 2021 Camurati-Engelmann syndrome, also known as progressive diaphyseal dysplasia, is a rare, autosomal dominant disease with a prevalence of one per million inhabitants. It generates mutations of the transforming growth factor beta, which participates in bone
Díaz Vallejo, Jhony Alejandro +3 more
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