Results 1 to 10 of about 600,797 (192)

Early Life Stress (ELS) Effects on Fetal and Adult Bone Development

open access: yesChildren, 2023
Early life stress (ELS) refers to harmful environmental events (i.e., poor maternal health, metabolic restraint, childhood trauma) occurring during the prenatal and/or postnatal period, which may cause the ‘epigenetic corruption’ of cellular and ...
Xena Giada Pappalardo   +6 more
doaj   +2 more sources

Signalling Pathways and Mechanical Forces Interact in Craniofacial Development and Homeostasis [PDF]

open access: yesInternational Dental Journal
Craniofacial bones, as essential components of the human head, play a crucial role in both physiological function and morphological evolution through their development and the maintenance of homeostasis.
Yifan Chen   +5 more
doaj   +2 more sources

Engineering Musculoskeletal Grafts for Multi-Tissue Unit Repair: Lessons From Developmental Biology and Wound Healing

open access: yesFrontiers in Physiology, 2021
In the musculoskeletal system, bone, tendon, and skeletal muscle integrate and act coordinately as a single multi-tissue unit to facilitate body movement.
Xu Zhang   +12 more
doaj   +2 more sources

Effects of Neurological Disorders on Bone Health

open access: yesFrontiers in Psychology, 2020
Neurological diseases, particularly in the context of aging, have serious impacts on quality of life and can negatively affect bone health. The brain-bone axis is critically important for skeletal metabolism, sensory innervation, and endocrine cross-talk
Ryan R. Kelly   +5 more
doaj   +2 more sources

Genetic basis for skeletal new bone formation [PDF]

open access: yesExploration of Musculoskeletal Diseases, 2023
Bone formation is a complex process that occurs throughout life, and is normally limited to the skeletal system. In bone formation, osteoprogenitor cells follow several developmental stages, including differentiation in osteoblasts, proliferation, matrix
Bruna Parreira   +3 more
doaj   +1 more source

Long Noncoding RNA GAS5: A New Factor Involved in Bone Diseases

open access: yesFrontiers in Cell and Developmental Biology, 2022
Long noncoding RNAs (lncRNAs), as an important type of RNA encoded in the human transcriptome, have shown to regulate different genomic processes in human cells, altering cell type and function.
Zi-Mo Zhou   +5 more
semanticscholar   +1 more source

Type H vessels: functions in bone development and diseases

open access: yesFrontiers in Cell and Developmental Biology, 2023
Type H vessels are specialized blood vessels found in the bone marrow that are closely associated with osteogenic activity. They are characterized by high expression of endomucin and CD31.
Xiaonan Liu   +4 more
semanticscholar   +1 more source

Madelung Deformity - Esthetic and Functional Outcomes from the Surgical Treatment with Distal Radial Dome Osteotomy and Vickers Ligament Section

open access: yesRevista Brasileira de Ortopedia, 2022
Objective The present study aimed to evaluate esthetic and functional outcomes from the surgical treatment of Madelung deformity in children. MethodThis is a retrospective study of pediatric patients with Madelung deformity who were surgically treated ...
Marcos Carvalho   +5 more
doaj   +2 more sources

Developmental principles informing human pluripotent stem cell differentiation to cartilage and bone.

open access: yesSeminars in Cell and Developmental Biology, 2021
Human pluripotent stem cells can differentiate into any cell type given appropriate signals and hence have been used to research early human development of many tissues and diseases.
Paul E. A. Humphreys   +5 more
semanticscholar   +1 more source

Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling

open access: yesNature Communications, 2021
Sclerosing bone disorder (SBD) includes a broad spectrum of monogenic diseases characterised by increased bone density. Here, the authors describe a previously unknown SBD in four families caused by mutations in TMEM53 and demonstrate the role this ...
Long Guo   +20 more
doaj   +1 more source

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