Results 21 to 30 of about 4,574,239 (286)

Developmental Bone Diseases in our Clinic

Orthopedics & Traumatology, 1975
Thirty-two patients with the developmental bone disease were registered in the department of orthopedic surgery, Tottori university school of medicine, for the past three years.The authors made a description of the clinical features and radiologic findings of the following patients.1) Chondrodysplasia punctata (an one-year-old young girl)2 ...
Kamihira, M., Ikemoto, K., Sumisaka, O.
openaire   +3 more sources

Lateral Mesoderm-Derived Mesenchymal Stem Cells With Robust Osteochondrogenic Potential and Hematopoiesis-Supporting Ability

Frontiers in Molecular Biosciences, 2022
Mesenchymal stem cells (MSCs) are among the most promising cell sources for the treatment of various diseases. Nonetheless, the therapeutic efficacy in clinical trials has been inconsistent due to the heterogeneity of MSCs, which may be partially ...
Yili Wei, Bin Wang, Lei Jia, Weijun Huang, Andy Peng Xiang, Andy Peng Xiang, Cong Fang, Xiaoyan Liang, Weiqiang Li, Weiqiang Li   +9 more
doaj   +1 more source

Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength [PDF]

, 2012
Osteoporosis is a common polygenic disease and global healthcare priority but its genetic basis remains largely unknown. We report a high-throughput multi-parameter phenotype screen to identify functionally significant skeletal phenotypes in mice ...
Gogakos Apostolos, Campbell, MJ, Anne H. van der Spek (145990), Campbell Michael J., Gogakos, A, Sunter, D, Williams, GR, David Sunter, Bassett, JHD, Boyde, A, Michael J. Campbell (5833), Sunter, D., Richard M Jacques, Project, S.M.G., Alan Boyde (146008), Croucher Peter I., Ramirez-Solis, R, Williams, G.R., Richard M. Jacques (145985), van der Spek Anne H., Holly Evans (145980), Bassett, J.H.D., Ryder, E, Edward Ryder (145998), Peter I. Croucher (146016), Graham R Williams, Evans, H, Bassett J. H. Duncan, Jacques, RM, Anne H van der Spek, J. H. Duncan Bassett (145971), Croucher, PI, Peter I Croucher, Project, SMG, Ryder, E., David Sunter (146002), Holly Evans, Gogakos, A., Jacqueline K. White (119191), Apostolos Gogakos (145975), Ramirez-Solis, R., Jacqueline K White, White Jacqueline K., Boyde, A., van der Spek, A.H., Evans, H., Michael J Campbell, Ramirez-Solis Ramiro, White, J.K., Jacques, R.M., J H Duncan Bassett, Apostolos Gogakos, Jacques Richard M., Croucher, P.I., Ryder Edward, Graham R. Williams (20148), Campbell, M.J., Evans Holly, Ramiro Ramirez-Solis (119181), Williams Graham R., Ramiro Ramirez-Solis, Edward Ryder, Alan Boyde, van der Spek, AH, Sanger Mouse Genetics Project, Sunter David, White, JK, Boyde Alan   +67 more
core   +1 more source

Engineering Musculoskeletal Grafts for Multi-Tissue Unit Repair: Lessons From Developmental Biology and Wound Healing

Frontiers in Physiology, 2021
In the musculoskeletal system, bone, tendon, and skeletal muscle integrate and act coordinately as a single multi-tissue unit to facilitate body movement.
Xu Zhang, Xu Zhang, Dan Wang, Dan Wang, Dan Wang, Dan Wang, King-Lun Kingston Mak, Rocky S. Tuan, Rocky S. Tuan, Dai Fei Elmer Ker, Dai Fei Elmer Ker, Dai Fei Elmer Ker, Dai Fei Elmer Ker   +12 more
doaj   +1 more source

Adjusting bone mass for differences in projected bone area and other confounding variables: an allometric perspective. [PDF]

, 2002
The traditional method of assessing bone mineral density (BMD; given by bone mineral content [BMC] divided by projected bone area [Ap], BMD = BMC/Ap) has come under strong criticism by various authors. Their criticism being that the projected bone "area"
Roger L. Holder, Nevill, AM, Holder, Roger, Maffulli, Nicola, Lau, Joseph T. F., Warren T. K. Lee, Lee, WTK, Jack C. Y. Cheng, Nevill, Alan M., Alan M. Nevill, Lee, Warren T. K., Lau, JTF, Joseph T. F. Lau, Maffulli, N, Leung, Sophie S. S. F., Holder, Roger L., Cheng, Jack C. Y., Nicola Maffulli, Cheng, JCY, Leung, SSSF, Sophie S. S. F. Leung   +20 more
core   +1 more source

Double non-contiguous fractures in a patient with spondylo-epiphyseal dysplasia with spinal ankylosis treated with open and percutaneous spinal fixation technique: a case report

BMC Research Notes, 2018
Background Patients with ankylosing spines are susceptible to developing spinal fractures even with minor trauma and can develop early or late neurological injuries.
Takahiro Ushijima, Kenichi Kawaguchi, Tadashi Matsumoto, Masaki Takagi, Tatsuro Kondoh, Gen Nishimura, Aritoshi Iida, Shiro Ikegawa, Nobuhiko Haga, Go Kato   +9 more
doaj   +1 more source

Mapping the immune microenvironment for mandibular alveolar bone homeostasis at single-cell resolution

Bone Research, 2021
Alveolar bone is the thickened ridge of jaw bone that supports teeth. It is subject to constant occlusal force and pathogens invasion, and is therefore under active bone remodeling and immunomodulation. Alveolar bone holds a distinct niche from long bone
Weimin Lin, Qiwen Li, Danting Zhang, Xiaohan Zhang, Xingying Qi, Qian Wang, Yaqian Chen, Caojie Liu, Hanwen Li, Shiwen Zhang, Yuan Wang, Bin Shao, Li Zhang, Quan Yuan   +13 more
doaj   +1 more source

Gaucher disease iPSC-derived osteoblasts have developmental and lysosomal defects that impair bone matrix deposition [PDF]

Human Molecular Genetics, 2018
Gaucher disease (GD) is caused by bi-allelic mutations in GBA1, the gene that encodes acid β-glucocerebrosidase (GCase). Individuals affected by GD have hematologic, visceral and bone abnormalities, and in severe cases there is also neurodegeneration. To shed light on the mechanisms by which mutant GBA1 causes bone disease, we examined the ability of ...
Leelamma M, Panicker, Manasa P, Srikanth, Thiago, Castro-Gomes, Diana, Miller, Norma W, Andrews, Ricardo A, Feldman   +5 more
openaire   +2 more sources

Maxillomandibular giant osteosclerotic lesions

Journal of Applied Oral Science, 2018
Giant Osteosclerotic Lesions (GOLs) are a group of rarely reported intraosseous lesions. Their precise diagnosis is important since they can be confused with malignant neoplasms.
Constantino LEDESMA-MONTES, María Dolores JIMÉNEZ-FARFÁN, Juan Carlos HERNÁNDEZ-GUERRERO   +2 more
doaj   +1 more source

Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring

Cell Reports, 2023
Summary: Maternal overnutrition increases inflammatory and metabolic disease risk in postnatal offspring. This constitutes a major public health concern due to increasing prevalence of these diseases, yet mechanisms remain unclear.
Michael J. Nash, Evgenia Dobrinskikh, Taylor K. Soderborg, Rachel C. Janssen, Diana L. Takahashi, Tyler A. Dean, Oleg Varlamov, Jon D. Hennebold, Maureen Gannon, Kjersti M. Aagaard, Carrie E. McCurdy, Paul Kievit, Bryan C. Bergman, Kenneth L. Jones, Eric M. Pietras, Stephanie R. Wesolowski, Jacob E. Friedman   +16 more
doaj   +1 more source