Results 21 to 30 of about 110,076 (245)

Caracterización de pacientes con enfermedades genéticas del esqueleto en un centro colombiano de remisión

Biomédica: revista del Instituto Nacional de Salud, 2017
Introducción. La prevalencia de talla baja en Colombia es de 10 %, aproximadamente. En el 2009, la International Skeletal Dysplasia Society incluyó 456 condiciones clínicas en su clasificación, con base en criterios bioquímicos, radiológicos y ...
Harvy Mauricio Velasco, Lina Patricia Buelvas   +1 more
doaj   +1 more source

A rare case of pancytopenia

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2023
Pancytopenia is a reduction in all the three peripheral blood cell lineages and presents as anemia, leukopenia, and thrombocytopenia. Aplastic anemia is pancytopenia with bone marrow hypocellularity.
Manaswini Edara, Varsha Bhatt, Shubhangi A Kanitkar, Aditi Patel   +3 more
doaj   +1 more source

From mesenchymal niches to engineered in vitro model systems: Exploring and exploiting biomechanical regulation of vertebrate hedgehog signalling

Materials Today Bio, 2022
Tissue patterning is the result of complex interactions between transcriptional programs and various mechanical cues that modulate cell behaviour and drive morphogenesis.
Fatmah I. Ghuloum, Colin A. Johnson, Natalia A. Riobo-Del Galdo, Mahetab H. Amer   +3 more
doaj   +1 more source

Age and Sexual Maturity Estimation of Stranded Striped Dolphins, Stenella coeruleoalba, Infected with Brucella ceti

Oceans, 2022
Age parameters in cetaceans allow examining conservation and studying individuals with growth affection. The age and sexual maturity of 51 stranded Stenella coeruleoalba striped dolphins from the Eastern Tropical Pacific (ETP) of Costa Rica, most ...
Karol Roca-Monge, Rocío González-Barrientos, Marcela Suárez-Esquivel, José David Palacios-Alfaro, Laura Castro-Ramírez, Mauricio Jiménez-Soto, Minor Cordero-Chavarría, Daniel García-Párraga, Ashley Barratclough, Edgardo Moreno, Gabriela Hernández-Mora   +10 more
doaj   +1 more source

Research progress on the role of transforming growth factor-β in tooth and craniofacial bone development and diseases

口腔疾病防治, 2022
Dental and craniofacial bone development is a highly coordinated process that is tightly controlled by genetics and influenced by complex environments.
CAI Lang, XIE Jing, ZHOU Xuedong
doaj   +1 more source

IGF2BP3 recognizes m6A to regulate histone-to-protamine replacement during mouse sperm development

The EMBO Journal
Post-meiotic development of spermatids is under the control of a sophisticated RNA metabolic network, wherein the N6-methyladenosine (m6A) modification of mRNA, and proteins that bind to it, exert crucial functions in regulating sperm development from ...
Dazhuang Wang, Zhenyi Huang, Yichun Zhou, Peiyan Chen, Gang Chang, Liwei Ke, Congying Jing, Haojie Yang, Jiexiang Zhao, Shaofang Ren, Yi Zheng, Yuhan Chen, Yunfan Xiang, Jun Liu, Mei Wang   +14 more
doaj   +1 more source

The Progress of CRISPR/Cas9-Mediated Gene Editing in Generating Mouse/Zebrafish Models of Human Skeletal Diseases

Computational and Structural Biotechnology Journal, 2019
Genetic factors play a substantial role in the etiology of skeletal diseases, which involve 1) defects in skeletal development, including intramembranous ossification and endochondral ossification; 2) defects in skeletal metabolism, including late bone ...
Nan Wu, Bowen Liu, Huakang Du, Sen Zhao, Yaqi Li, Xi Cheng, Shengru Wang, Jiachen Lin, Junde Zhou, Guixing Qiu, Zhihong Wu, Jianguo Zhang   +11 more
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

A monoallelic variant in CCN2 causes an autosomal dominant spondyloepimetaphyseal dysplasia with low bone mass

Bone Research
Cellular communication network factor 2 (CCN2) is a secreted extracellular matrix-associated protein, and its aberrantly increased expression has been implicated in a diversity of diseases involving pathological processes of fibrosis, chronic ...
Shanshan Li, Rui Shao, Shufa Li, Jiao Zhao, Qi Deng, Ping Li, Zhanying Wei, Shuqin Xu, Lin Chen, Baojie Li, Weiguo Zou, Zhenlin Zhang   +11 more
doaj   +1 more source

Research progress on the mechanism of the Hedgehog signaling pathway during mandibular development [PDF]

口腔疾病防治
The source and process of mandible development are significantly different from those of other bones in the body, and abnormal development can lead to various bone-related diseases, seriously affecting the quality of life of patients.
XU Yao, LI Wenjin
doaj   +1 more source