Deciphering Myostatin’s Regulatory, Metabolic, and Developmental Influence in Skeletal Diseases
Frontiers in Genetics, 2021 Current research findings in humans and other mammalian and non-mammalian species support the potent regulatory role of myostatin in the morphology and function of muscle as well as cellular differentiation and metabolism, with real-life implications in ...
Catherine L Omosule, C. Phillips
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Zebrafish and medaka as models for biomedical research of bone diseases.
Developmental Biology, 2020 The identification of disease-causing mutations has in recent years progressed immensely due to whole genome sequencing approaches using patient material.
L. Lleras-Forero +2 more
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Nanotechnology in the targeted drug delivery for bone diseases and bone regeneration [PDF]
, 2013 Nanotechnology is a vigorous research area and one of its important applications is in biomedical sciences. Among biomedical applications, targeted drug delivery is one of the most extensively studied subjects. Nanostructured particles and scaffolds have
Chen, Jiezhong +3 more
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Mesoporous Silica Nanoparticles for the Treatment of Complex Bone Diseases: Bone Cancer, Bone Infection and Osteoporosis [PDF]
, 2020 Bone diseases, such as bone cancer, bone infection and osteoporosis, constitute a major issue for modern societies as a consequence of their progressive ageing.
María Vallet-Regí +5 more
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Developmental Bone Diseases in our Clinic
Orthopedics & Traumatology, 1975 Thirty-two patients with the developmental bone disease were registered in the department of orthopedic surgery, Tottori university school of medicine, for the past three years.The authors made a description of the clinical features and radiologic findings of the following patients.1) Chondrodysplasia punctata (an one-year-old young girl)2 ...
Kamihira, M., Ikemoto, K., Sumisaka, O.
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Frontiers in Molecular Biosciences, 2022 Mesenchymal stem cells (MSCs) are among the most promising cell sources for the treatment of various diseases. Nonetheless, the therapeutic efficacy in clinical trials has been inconsistent due to the heterogeneity of MSCs, which may be partially ...
Yili Wei +9 more
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Bone Angiogenesis and Vascular Niche Remodeling in Stress, Aging, and Diseases
Frontiers in Cell and Developmental Biology, 2020 The bone marrow (BM) vascular niche microenvironments harbor stem and progenitor cells of various lineages. Bone angiogenesis is distinct and involves tissue-specific signals.
Sina Stucker +3 more
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Adjusting bone mass for differences in projected bone area and other confounding variables: an allometric perspective. [PDF]
, 2002 The traditional method of assessing bone mineral density (BMD; given by bone mineral content [BMC] divided by projected bone area [Ap], BMD = BMC/Ap) has come under strong criticism by various authors. Their criticism being that the projected bone "area"
Roger L. Holder +20 more
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The Role of Bone-Derived Exosomes in Regulating Skeletal Metabolism and Extraosseous Diseases
Frontiers in Cell and Developmental Biology, 2020 Bone-derived exosomes are naturally existing nano-sized extracellular vesicles secreted by various cells, such as bone marrow stromal cells, osteoclasts, osteoblasts, and osteocytes, containing multifarious proteins, lipids, and nucleic acids ...
Huili Lyu +4 more
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Interactions of porphyromonas gingivalis with bone marrow cells: implications on mediators of bone resorption [PDF]
, 2012 PhDPeriodontitis is a multi-factorial disease characterised by the loss of connective tissue and underlying alveolar bone leading to the loss of teeth. Porphyromonas gingivalis (P.
Reddi, Durga
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