Results 41 to 50 of about 575 (86)

Differences in inflammatory markers, mitochondrial function, and synaptic proteins in male and female Alzheimer's disease post mortem brains

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION Inflammation and mitochondrial impairments are suggested to underlie Alzheimer's disease (AD) development. This study examined whether metabolic, synaptic, and inflammatory markers in AD differed from non‐demented brains.
Alex J. T. Yang, Ahmad Mohammad, Robert W. E. Crozier, Lucas Maddalena, Evangelia Tsiani, Adam, J. MacNeil, Gaynor E. Spencer, Aleksandar Necakov, Paula Duarte‐Guterman, Jeffery Stuart, Rebecca E. K. MacPherson   +11 more
wiley   +1 more source

Automated MRI Segmentation of Brainstem Nuclei Critical to Consciousness

Human Brain Mapping, Volume 46, Issue 14, 01 October 2025.
To advance coma and consciousness research, we developed a method for segmenting brainstem ascending arousal network nuclei from MRI scans. We validated automated segmentations of these nuclei in normative brain scans from multiple MRI modalities, as well as in patients with Alzheimer's disease and traumatic brain injury.
Mark D. Olchanyi, Jean Augustinack, Robin L. Haynes, Laura D. Lewis, Nicholas Cicero, Jian Li, Christophe Destrieux, Rebecca D. Folkerth, Hannah C. Kinney, Bruce Fischl, Emery N. Brown, Juan Eugenio Iglesias, Brian L. Edlow   +12 more
wiley   +1 more source

Co‐pathology in Alzheimer's disease and Lewy body disease and its association with neuropsychiatric symptoms

Alzheimer's &Dementia, Volume 21, Issue 9, September 2025.
Abstract BACKGROUND Mixed neuropathology is common in dementia, but the clinical implications for neuropsychiatric symptoms (NPSs) are not well characterized. METHODS In a population‐based post mortem study, cases with Alzheimer's disease neuropathological change (ADNC) and Lewy body disease (LBD) were identified with any comorbid neuropathology ...
Lucy L. Gibson, Lea T. Grinberg, Victor R. Paes, Christoph Mueller, Renata E. P. Leite, Paula Villela Nunes, Alberto F. O. Justo, Carlos A. Pasqualucci, Eduardo Ferriolli, Dag Aarsland, Claudia K. Suemoto   +10 more
wiley   +1 more source

No association between histopathology and neurophysiology in surgical specimens from pediatric focal epilepsy patients

Epilepsia, Volume 66, Issue 9, Page 3168-3179, September 2025.
Abstract Objective Focal epilepsy is caused by focal brain pathologies sometimes with involvement of surrounding or distant tissue. However, within the epileptogenic zone (EZ), which can be resected to cure epilepsy, the contribution of histopathological cells to epileptogenicity remains unknown.
Nicolás von Ellenrieder, Mariam Alrashid, Kenneth Myers, Bradley Osterman, Elisabeth Simard‐Tremblay, Jason Karamchandani, Marie‐Christine Guiot, Jean Gotman, Roy W. R. Dudley   +8 more
wiley   +1 more source

Resource availability for CNS tumor diagnostics in the Asian Oceanian region: A survey by the Asian Oceanian Society of Neuropathology committee for Adapting Diagnostic Approaches for Practical Taxonomy in Resource‐Restrained Regions (AOSNP‐ADAPTR)

Brain Pathology, Volume 35, Issue 4, July 2025.
Asian Oceanian Society of Neuropathology‐Adapting Diagnostic Approaches for Practical Taxonomy in Resource‐Restrained Regions survey provides an overview of in‐house/ local and outsourcing resources in Asian Oceanian region for brain tumor diagnostics according to World Health Organization classification of Central Nervous System tumors.
Chitra Sarkar, Shilpa Rao, Vani Santosh, Maysa Al‐Hussaini, Sung Hye Park, Tarik Tihan, Michael E. Buckland, Ho‐Keung Ng, Takashi Komori   +8 more
wiley   +1 more source

cIMPACT‐NOW update 10: Recommendations for defining new types for central nervous system tumor classification

Brain Pathology, Volume 35, Issue 6, November 2025.
Cynthia Hawkins, Kenneth Aldape, David Capper, Andreas von Deimling, Caterina Giannini, Mark R. Gilbert, Thomas S. Jacques, David Jones, Takashi Komori, David N. Louis, Sabine Mueller, MacLean Nasrallah, Brent A. Orr, Arie Perry, Stefan M. Pfister, Felix Sahm, Chitra Sarkar, Matija Snuderl, David Solomon, Pascale Varlet, Pieter Wesseling, Guido Reifenberger   +21 more
wiley   +1 more source

Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executive summary of recommendations for primary care

Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri, Bradford C. Dickerson, Carolyn Clevenger, Jason Karlawish, David Knopman, Pei‐Jung Lin, Mary Norman, Chiadi Onyike, Mary Sano, Susan Scanland, Maria Carrillo   +10 more
wiley   +1 more source

Diagnostic Accuracy of 1H‐MRS Using PRESS and MEGA‐PRESS Techniques in the Preoperative Grading of Patients With Gliomas

Journal of Magnetic Resonance Imaging, Volume 61, Issue 6, Page 2480-2488, June 2025.
Background Edited MRS technique such as MEshcher‐GArwood Point RESolved Spectroscopy (MEGA‐PRESS) can determine isocitrate dehydrogenase mutation (IDH) mutation status in patients with gliomas but its accuracy in assessing glioma grade has not yet been formally evaluated.
Maria L. Brun‐Vergara, Gerd Melkus, Santanu Chakraborty, Nader Zakhari, Carlos Torres, Fahad AlKherayf, Leya Ghantous, Rebecca Thornhill, John Woulfe, Gerard H. Jansen, Thanh B. Nguyen   +10 more
wiley   +1 more source

Canadian Association of Neuropathologists [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2008
openaire   +1 more source