Results 131 to 140 of about 1,614,127 (301)

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

Efectos de implantes, olaquindox y sexo sobre las características de la canal de cerdos

Revista Científica, 2010
Se utilizaron 54 cerdos Landrace y Yorkshire en un diseño completamente aleatorizado. El análisis de varianza-covarianza por cuadrados mínimos para cada raza, incluyo los efectos del sexo (hembras y machos castrados), tratamiento (DES = implante de
Nelson Huerta Leidenz, Enio Wilhelm, Guillermo Ríos Fuenmayor, Angel Páez, Edmundo Rincón, Nancy Jerez Timaure   +5 more
doaj  

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

Variación de características en pie y en canal de bovinos en Venezuela y su relación con el rendimiento de cortes valiosos

Revista Científica, 2010
Una prueba de desposte se condujo con diferentes clases de bovinos (658 toros, 346 novillos, 59 vacas y 49 novillas), evaluados en los corrales, en la línea de faena y en las cavas de almacenamiento de un matadero comercial, para un total de 20 ...
Nelson Huerta Leidenz, Oneida Morón Fuenmayor   +1 more
doaj  

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

Sustitución parcial de harina de soja y maíz molido por garbanzo de descarte en la respuesta productiva y rendimiento en canal de codorniz japonesa

Revista Científica, 2011
Para determinar el efecto de la sustitución parcial de harina de soja y grano de maíz molido por el subproducto garbanzo de descarte en la respuesta productiva de codorniz japonesa (Coturnix coturnix japonica) en engorde se utilizaron 1.125 codornices ...
Jesús José Portillo Loera, Carlos Bell Castro Tamayo, Jesús Francisco Obregón, Alejandro Plascencia Jorquera, Francisco Gerardo Ríos Rincón, Diana Karely Suárez Guerrero   +5 more
doaj  

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Predicción del rendimiento en cortes de carnicería de bovinos venezolanos

Revista Científica, 2010
Datos de cortes obtenidos de ganado bovino (hasta 1197 observaciones) fueron utilizados para desarrollar ecuaciones de predicción del rendimiento en cortes de valor (RCD), Porcentaje de hueso (PHUESO) y recortes de grasa (PGRASA).
Oscar Atencio-Valladares, Nelson Huerta-Leidenz N, Nancy Jerez-Timaure N   +2 more
doaj  

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source