Results 181 to 190 of about 1,614,127 (301)

A Mini‐Spidroin Forms High‐Performance Artificial Spider Silk via Edge‐Cysteine–Locked β‐Sheet Assembly

Advanced Science, EarlyView.
Cysteine‐engineered mini‐spidroins (∼33 kDa) undergo phosphate‐induced liquid–liquid phase separation (LLPS), where disulfide bonds lock partially aligned polyA segments. Subsequent microfluidic spinning promotes directional β‐sheet crystallization, producing fibers with 531 MPa strength and 182 MJ/m3 toughness.
Min Li, Huan Chen, Qi Zhang, Xiaoyun Xu, Yini Zheng, Chunyu Lyu, Weibin Jia, Jun Fan, Fu‐Rong Chen, Wei Liu, Jinlian Hu   +10 more
wiley   +1 more source

Innervation Drives Postembryonic Expansion of the Zebrafish Anterior Lateral Line System. [PDF]

J Comp Neurol
Christiansen TJ, Venkataraman V, Prince VE.   +2 more
europepmc   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Impact of Downward Load and Rotational Kinematics on Root Canal Instrumentation with a Heat-Treated Nickel-Titanium Rotary Instrument. [PDF]

Materials (Basel)
Yamamoto R, Maki K, Kimura S, Omori S, Hirano K, Ebihara A, Yahata Y, Okiji T.   +7 more
europepmc   +1 more source

F13A1‐Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway

Advanced Science, EarlyView.
In fatty liver disease, hepatocytes exposed to palmitate release S1P, which activates calcium signaling in macrophages. Elevated calcium enhances the activity of F13A1, driving PKM2 dimerization. The PKM2 dimers cause Warburg effect, translocate to the nucleus, cooperate with HIF1A, and upregulate IL1B expression, ultimately promoting classical ...
Qianrang Lu, Meiching Ong, Xuewen Yi, Muqiong Xing, Xinyao Tian, Ke Zhang, Ling Lu, Hao Wang, Xiaohan Lin, Jun Fang, Aibo Mu, Jiaying Cao, Jingyu Jiang, Feng Gao, Hongjun Li, Baohong Wang, Qi Ling   +16 more
wiley   +1 more source

Cortical bone porosity is spatially heterogeneous and VEGF dependent in male bone.

Dis Model Mech
Trend J, Keen J, Sharma A, Sharma A, Michels L, Goggin P, Schneider P, Deinhardt K, Clarkin CE.   +8 more
europepmc   +1 more source

Endoscopic endonasal surgery for optic nerve sheath and optic canal meningiomas: 2D operative video. [PDF]

Neurosurg Focus Video
Burgos-Sosa E, Xu Y, Lamano J, Vigo V, Banu MA, Chang M, Liu C, Fernandez-Miranda JC.   +7 more
europepmc   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

Paramedian tuberculum sellae meningioma: tumor resection and optic canal unroofing via contralateral supraorbital eyebrow approach. [PDF]

Neurosurg Focus Video
Ranjan R, Das KK, Gogoi S, Madheshiya S, Srivastava AK.   +4 more
europepmc   +1 more source

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

Advanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang, Jun Zhang, Yan Wang, Guoping Chen, Kehui Yuan, Yuan He, Chenchen Li, Sumaira Hanif, Yang Yang, Yanli Wang, Pir Muhammad   +10 more
wiley   +1 more source