Results 31 to 40 of about 605,488 (308)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Correspondencias & AnálisisEn la era digital actual, el correo electrónico ha mantenido su relevancia como medio de comunicación institucional a pesar de la aparición de tecnologías más avanzadas. Este artículo revisa críticamente su papel bajo el marco de la Teoría de la Riqueza
Carla Oliva
doaj +1 more source
Multiple unilateral accessory mandibular foramina- a case report
National Journal of Clinical Anatomy, 2012 Accessory foramina in the mandible are known to transmit branches of nerves supplying the roots of the teeth. The mandibular foramen is present on the inner surface of the ramus of the mandible which transmits the inferior alveolar nerve.
Seema, Anupama Mahajan
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
EFFECT OF FEEDING DINNING ROOM AND KITCHEN WASTE ON GROWTH PERFORMANCE OF GROWING PIGS
Tropical and Subtropical Agroecosystems, 2014 This research used 41 growing backyard piglets (11.47 ± 1.2 kg BW) fed for 22 d and assigned at random to three treatment (T) groups, respectively (T1 to T3) with three repetitions. The proportion of commercial concentrate (CC) to kitchen waste (DW) was:
Guadalupe RamÃrez Zúñiga +7 more
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source