Results 41 to 50 of about 605,488 (308)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Revista Científica, 2010 Para evaluar el efecto de la incorporación de la harina de follaje de yuca (HFY) en niveles crecientes (0; 2,5; 5 y 7,5%) en raciones alimenticias para pollos de engorde sobre las características al sacrificio y el rendimiento en canal y en cortes ...
Jacqueline Trómpiz +5 more
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Shuili Shuiyun Gongcheng Xuebao, 2021 The reconstruction and extension project of the long-distance water transfer canal in Northern Xinjiang is key to water delivery efficiency and project safety.
CHEN Bowen, HUANG Yinghao
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
A propósito de la comunicación verbal
Forma y Función, 2009 El presente artículo es el resultado de un estudio de la comunicación verbal teniendo en cuenta la visión propuesta por el modelo inferencial. El objetivo del texto es ofrecer una descripción detallada de cada uno de los elementos que intervienen en él ...
Fajardo Uribe Luz Amparo
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Revista Iberoamericana de Bioeconomía y Cambio Climàtico, 2019 En este estudio se analiza la relación entre el espesor de grasa subcutánea (EGS), espesor muscular (EM) y espesor de grasa subcutánea y espesor muscular juntos (EGSM), medidos con ultrasonido en un solo punto anatómico de cerdos vivos y los parámetros ...
Santiago Hernández Zapata +3 more
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Protection system against water at the open pit Gacko with collective water collector as the capital structure [PDF]
Mining and Metallurgy Engineering Bor, 2016 Protection of the open pit against water is very important, especially if the open pit is located in the complex conditions regarding protection of the open pit against water.
Doderović Aleksandar +2 more
doaj +1 more source