Results 81 to 90 of about 273,804 (259)
Revue des Énergies Renouvelables, 2017 Une investigation numérique du comportement hydrodynamique et thermique de l’écoulement d’air dans un canal rectangulaire munie des chicanes sous forme aile est effectuée dans le présent papier. L’effet du l’insertion des chicanes a été analysé.
A. Youcef
doaj
Advanced Science, EarlyView.This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche +21 more
wiley +1 more source
Advanced Science, EarlyView.PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li +17 more
wiley +1 more source
Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly
Advanced Science, EarlyView.Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao +5 more
wiley +1 more source
CT&F Ciencia, Tecnología & Futuro, 2009 Some well pressure tests conducted in channelized systems which result from either fluvial deposition or faulting, cannot be completely interpreted by conventional techniques, since variation in facies or reservoir width are not normally recognized yet ...
Freddy-Humberto Escobar +2 more
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Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
Advanced Science, EarlyView.This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source
Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging
Advanced Science, EarlyView.Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre +12 more
wiley +1 more source
LA CUEVA NEGRA (FORTUNA, MURCIA). EXCAVACIÓN DE TANTEO. DICIEMBRE DE 1985
Antigüedad y Cristianismo, 1996 Se presentan los resultados de la actuación arqueológica desarrollada en el paraje de la Cueva Negra, que no ha dado ningún material de época romana para poder relacionarlo con los grafitos de la cueva, aunque sí se ha registrado una presencia abundante ...
Manuel Amante Sánchez
doaj
Recreation- and sport-led regeneration of urban water infrastructure
Frontiers in Sports and Active LivingToday, cities are to a growing extent looking for solutions for how urban infrastructure, like former industrial sites, can be developed into facilities for sport and recreation, as well as tourism. One example of such infrastructure is canals and former
Karin Book
doaj +1 more source
Advanced Science, EarlyView.Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider +20 more
wiley +1 more source