Results 161 to 170 of about 4,028,214 (240)

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao, Long He, Yu Lu, Zanglong Deng, Hongzhen Wei, Yunpeng Zhang, Ming Yang, Tao Yin   +7 more
wiley   +1 more source

Assessment of canal centering and dentinal integrity following root canal preparation with different NiTi file systems: An in vitro CBCT and stereomicroscopic study. [PDF]

Medicine (Baltimore)
Baba SM, Nik Abdul Ghani NR, Alqarni M, Abdullah JY, Shafi S.   +4 more
europepmc   +1 more source

Canal Boat Under Bridge

One black and white photographic print of a canal boat passing under a bridge on a canal, probably the Ohio and Erie Canal in eastern Ohio. A person can be seen standing on top of the boat while several buildings can be seen lining the bank of the canal ...
Canal Society of Ohio
core  

ZMIZ2–DUX4–LGR5 Signaling Axis Maintains Stemness Properties and Facilitates Docetaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study identifies ZMIZ2 as a therapeutic target for docetaxel‐resistant triple‐negative breast cancer, sustaining cancer stemness‐associated properties and docetaxel resistance. ZMIZ2 upregulation enhances DUX4‐mediated LGR5 activation through the SWI/SNF components BRG1 and BAF57.
Xueting Gan, Shulei Sun, Ran Hu, Yuheng Feng, Xinhao Wu, Fangqi Liu, Xuyong Lin, Xiupeng Zhang, Xuezhu Rong, Qiang Han   +9 more
wiley   +1 more source

Micro-CT Analysis of Solvent Use and Apical Enlargement in the Retreatment of S-Shaped Root Canals of Mandibular Molars. [PDF]

Int Endod J
Leal RMS, Campos MCBP, Copelli FA, Oda LY, Rodrigues CT, Cavenago BC, Silva EJNL.   +6 more
europepmc   +1 more source

Canal-era House 1

One color photographic slide of a canal-era house standing next to the canal, probably the Ohio and Erie Canal, which can be seen in the background to the left.
Canal Society of Ohio
core  

The Characteristics of Tumor Microenvironment by the Single Cell Profile in Endometrial Cancer of no Specific Molecular Profile (NSMP) Subtype

Advanced Science, EarlyView.
A subset of tumor‐associated macrophages (TAMs) characterized by SPP1 expression is discovered, which may remodel the tumor microenvironment by potentially promoting CD4+ T cell stress and maintaining epithelial cell stemness through SPP1‐CD44, thereby potentially contributing to the proliferation and migration of tumor cells, which has been verified ...
Xinhui Yuan, Zhengyao Zhai, Chuyu Jing, Wei Zhang, Wenjuan Tian, Yulan Ren   +5 more
wiley   +1 more source

Geometric response of curved mandibular molars to NiTi instrumentation. [PDF]

Bioinformation
Masreen J, Badami V, Badaka B, Waseem SM, Sriharsha A, V YS.   +5 more
europepmc   +1 more source

Canal Lock

One black and white photographic slide of a canal lock on a canal, probably the Ohio and Erie Canal in eastern Ohio. Water flows through the struncture and into the foreground while the towpath lines the water on the right.
Canal Society of Ohio
core  

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source